Results 221 to 230 of about 249,320 (341)

On‐Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles

Small, EarlyView.
A microfluidic platform integrates mRNA synthesis, purification, and LNPs formulation in a continuous, streamlined process. DNA templates are transcribed on‐chip, producing mRNA that is immediately purified and encapsulated into LNPs. This approach enables rapid, scalable production of mRNA‐LNP formulations for research or therapeutic applications ...
Shai Zilberzwige‐Tal, Aviad Levin, Assaf Ezra, Uri Elia, Gal Finkelstein‐Zuta, Topaz Kreiser, Lihi Gershon, Meir Goldsmith, Edo Kon, Yoav Navon, Ofer Cohen, Tuomas PJ Knowles, Dan Peer, Ehud Gazit   +13 more
wiley   +1 more source

Systematic identification of disease-causing promoter and untranslated region variants in 8040 undiagnosed individuals with rare disease. [PDF]

Genome Med
Martin-Geary AC, Blakes AJM, Dawes R, Findlay SD, Lord J, Dong S, Walker S, Talbot-Martin J, Wieder N, D'Souza EN, Fernandes M, Hilton S, Lahiri N, Campbell C, Jenkinson S, DeGoede CGEL, Anderson ER, Candler T, Firth H, Burge CB, Sanders SJ, Ellingford J, Baralle D, Banka S, Whiffin N.   +24 more
europepmc   +1 more source

A motif in the 5'untranslated region of messenger RNAs regulates protein synthesis in a S6 kinase-dependent manner. [PDF]

Adv Biol Regul, 2023
Shin HC, Bochkov YA, Kim K, Gern JE, Jarjour NN, Esnault S.   +5 more
europepmc   +1 more source

Frequency of the 20210 G→A Mutation in the 3′-Untranslated Region of the Prothrombin Gene in 35 Cases of Cerebral Venous Thrombosis

, 1998
V. Biousse, J. Conard, Chantal Brouzes, M.H. Horellou, Alain Améri, Marie‐Germaine Bousser   +5 more
openalex   +1 more source

Identification of a Conserved and Functional Iron-responsive Element in the 5′-Untranslated Region of Mammalian Mitochondrial Aconitase [PDF]

, 1996
Hae‐Yeong Kim, Timothy LaVaute, Kazuhiro Iwaï, Richard D. Klausner, Tracey A. Rouault   +4 more
openalex   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
wiley   +1 more source

Correction to "Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5'-Untranslated Region of SARS-CoV-2". [PDF]

J Am Chem Soc
Mertinkus KR, Oxenfarth A, Richter C, Wacker A, Mata CP, Carazo JM, Schlundt A, Schwalbe H.   +7 more
europepmc   +1 more source

A Functional Single Nucleotide Polymorphism in the 3' Untranslated Region of the Porcine JARID2 Gene Is Associated with Aggressive Behavior of Weaned Pigs after Mixing. [PDF]

Int J Mol Sci, 2023
Yang H, Zhang C, Chao X, Zhao J, Liu M, Chen J, Liu S, Wang T, Muhammad A, Schinckel AP, Zhou B.   +10 more
europepmc   +1 more source

Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen [PDF]

, 1988
Hinoda, Yuji, Neumaier, Michael, Riggs, Arthur D., Shively, John E., Shively, Louise, Zimmermann, Wolfgang   +5 more
core  

The 3' untranslated region of the B19 parvovirus capsid protein mRNAs inhibits its own mRNA translation in nonpermissive cells

, 1997
C. Pallier, Anna Greco, Janine Le Junter, Ali Saı̈b, Isabelle Vassias, F. Morinet   +5 more
openalex   +1 more source