Results 221 to 230 of about 246,994 (340)

KYNA Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via FTO‐Dependent m6A Demethylation of LATS1

open access: yesCell Proliferation, EarlyView.
Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng   +10 more
wiley   +1 more source

Dystrophin isoform deficiency and upper‐limb and respiratory function in Duchenne muscular dystrophy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Mary Chesshyre, Deborah Ridout, Georgia Stimpson, Valeria Ricotti, Silvana De Lucia, Erik H Niks, Volker Straub, Laurent Servais, Jean‐Yves Hogrel, Giovanni Baranello, Adnan Manzur, UK NorthStar Clinical Network and Francesco Muntoni* on behalf of the iMDEX network.
Mary Chesshyre   +176 more
wiley   +1 more source

Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3' untranslated region mutations. [PDF]

open access: yesCell Rep, 2023
Schuster SL   +13 more
europepmc   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina   +8 more
wiley   +1 more source

5'-untranslated region sequences enhance plasmid-based protein production in Sulfolobus acidocaldarius. [PDF]

open access: yesFront Microbiol
Kuschmierz L   +6 more
europepmc   +1 more source

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