Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng+10 more
wiley +1 more source
Correction to "Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5'-Untranslated Region of SARS-CoV-2". [PDF]
Mertinkus KR+7 more
europepmc +1 more source
A motif in the 5'untranslated region of messenger RNAs regulates protein synthesis in a S6 kinase-dependent manner. [PDF]
Shin HC+5 more
europepmc +1 more source
Identification of two proteins that bind to a pyrimidine-rich sequence in the 3'-untranslated region of GAP-43 mRNA [PDF]
Nina Irwin+3 more
openalex +1 more source
Dystrophin isoform deficiency and upper‐limb and respiratory function in Duchenne muscular dystrophy
Mary Chesshyre, Deborah Ridout, Georgia Stimpson, Valeria Ricotti, Silvana De Lucia, Erik H Niks, Volker Straub, Laurent Servais, Jean‐Yves Hogrel, Giovanni Baranello, Adnan Manzur, UK NorthStar Clinical Network and Francesco Muntoni* on behalf of the iMDEX network.
Mary Chesshyre+176 more
wiley +1 more source
Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3' untranslated region mutations. [PDF]
Schuster SL+13 more
europepmc +1 more source
Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina+8 more
wiley +1 more source
5'-untranslated region sequences enhance plasmid-based protein production in Sulfolobus acidocaldarius. [PDF]
Kuschmierz L+6 more
europepmc +1 more source
The 3'‑untranslated region of XB130 regulates its mRNA stability and translational efficiency in non‑small cell lung cancer cells. [PDF]
Wang Q+8 more
europepmc +1 more source