A functional role for the conserved protonatable hairpins in the 5' untranslated region of turnip yellow mosaic virus RNA [PDF]
Koen Hellendoorn+2 more
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N6‐methyladenosine (m6A) is a frequently occurring RNA modification that has emerged as an important player in tumour development through post‐transcriptional gene regulation. In this study, we found that IGF2BP3 modulates HSP90AB1 expression in an m6A modification‐dependent manner, activating the PI3K/AKT‐signaling pathway, and thereby promoting the ...
Xiaoqing Chen+10 more
wiley +1 more source
Pathogenic Variant in the 5'-Untranslated Region of <i>GCH1</i> and Clinical Heterogeneity in a Chinese Family with Dopa-Responsive Dystonia. [PDF]
Li Y, Li M, Liu L, Sun Q, Yang G.
europepmc +1 more source
Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser+9 more
wiley +1 more source
Genetic Variants and Their Putative Effects on microRNA-Seed Sites: Characterization of the 3' Untranslated Region of Genes Associated with Temperament. [PDF]
Ruiz-De-La-Cruz G+8 more
europepmc +1 more source
The 3' untranslated region of IL-1beta regulates protein production. [PDF]
Jeffrey A. Kern+2 more
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Identification of a minimal strong translation enhancer within the 5'-untranslated region of <i>OsMac3</i> mRNA. [PDF]
Aoki-Mutsuro H+9 more
europepmc +1 more source
Characterization of a FourU RNA Thermometer in the 5' Untranslated Region of Autolysin Gene blyA in the Bacillus subtilis 168 Prophage SPβ. [PDF]
Tong AY+4 more
europepmc +1 more source
Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock
Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány+6 more
wiley +1 more source
Vigilin, a Ubiquitous Protein with 14 K Homology Domains, Is the Estrogen-inducible Vitellogenin mRNA 3′-Untranslated Region-binding Protein [PDF]
Robin E. Dodson, David J. Shapiro
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