Results 241 to 250 of about 246,994 (340)

The N6‐methyladenosine reader IGF2BP3 promotes bladder cancer progression through enhancing HSP90AB1 expression

open access: yesThe FEBS Journal, EarlyView.
N6‐methyladenosine (m6A) is a frequently occurring RNA modification that has emerged as an important player in tumour development through post‐transcriptional gene regulation. In this study, we found that IGF2BP3 modulates HSP90AB1 expression in an m6A modification‐dependent manner, activating the PI3K/AKT‐signaling pathway, and thereby promoting the ...
Xiaoqing Chen   +10 more
wiley   +1 more source

Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44

open access: yesThe FEBS Journal, EarlyView.
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser   +9 more
wiley   +1 more source

Genetic Variants and Their Putative Effects on microRNA-Seed Sites: Characterization of the 3' Untranslated Region of Genes Associated with Temperament. [PDF]

open access: yesGenes (Basel), 2023
Ruiz-De-La-Cruz G   +8 more
europepmc   +1 more source

The 3' untranslated region of IL-1beta regulates protein production. [PDF]

open access: bronze, 1997
Jeffrey A. Kern   +2 more
openalex   +1 more source

Identification of a minimal strong translation enhancer within the 5'-untranslated region of <i>OsMac3</i> mRNA. [PDF]

open access: yesPlant Biotechnol (Tokyo)
Aoki-Mutsuro H   +9 more
europepmc   +1 more source

Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock

open access: yesThe FEBS Journal, EarlyView.
Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány   +6 more
wiley   +1 more source

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