Results 261 to 270 of about 249,320 (341)

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, EarlyView.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

Four SNPs in the untranslated region of the NOTCH2 gene involved in reproductive traits in fertile and anestrum Holstein Friesian cattle. [PDF]

BMC Vet Res
Mahmoud KGM, Sosa ASA, Darwish HRH, Ibrahim S, Hasanain MH, Almadaly EA, Sakr AM, Shams ASE, Ilie DE.   +8 more
europepmc   +1 more source

Transdifferentiation of chicken embryonic cells into muscle cells by the 3' untranslated region of muscle tropomyosin.

, 1995
Thomas J. L’Ecuyer, Paul C. Tompach, E Morris, Alice Fulton   +3 more
openalex   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Detecting microsatellite instability by length comparison of microsatellites in the 3' untranslated region with RNA-seq. [PDF]

Brief Bioinform
Choi JW, Lee JO, Lee S.
europepmc   +1 more source

Posttranscriptional Destabilization of the Bradykinin B1 Receptor Messenger RNA: Cloning and Functional Characterization of the 3′-Untranslated Region

, 1999
Xiaofeng Zhou, Gregory N. Prado, Minhua Chai, Xionghu Yang, Linda Taylor, Péter Polgàr   +5 more
openalex   +1 more source

The 3' untranslated region of IL-1beta regulates protein production. [PDF]

, 1997
Jeffrey A. Kern, L J Warnock, J. D. McCafferty   +2 more
openalex   +1 more source

Exploring the Therapeutic Potential of MIR‐140‐3p in Osteoarthritis: Targeting CILP and Ferroptosis for Novel Treatment Strategies

Cell Proliferation, EarlyView.
Global landscape. ABSTRACT Osteoarthritis (OA) is a prevalent and debilitating joint disorder that affects millions of individuals worldwide, severely impairing mobility, independence, and quality of life. Emerging evidence suggests that ferroptosis is a critical factor in OA pathogenesis.
Feng Ma, Lexin Wang, Hao Chi, Xinyi Li, Yaoqin Xu, Kexin Chen, Jingfan Zhou, Runqin Yang, Jie Liu, Ke Xu, Xiaoling Yang   +10 more
wiley   +1 more source

Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5'-Untranslated Region of SARS-CoV-2. [PDF]

J Am Chem Soc
Mertinkus KR, Oxenfarth A, Richter C, Wacker A, Mata CP, Carazo JM, Schlundt A, Schwalbe H.   +7 more
europepmc   +1 more source

A four base pair insertion polymorphism in the 3′ untranslated region of the COL1A1 gene is highly informative for null-allele testing in patients with osteogenesis imperfecta type I

, 1998
Lieve Nuytinck, Chris W. Coppin, Anne De Paepe   +2 more
openalex   +2 more sources