Results 311 to 320 of about 249,320 (341)

Gaining insights into epigenetic memories through artificial intelligence and omics science in plants

Journal of Integrative Plant Biology, EarlyView.
This review explores how artificial intelligence and machine learning predict plant behavior in response to environmental stress by modeling molecular regulatory networks of plant stress responses. Their combined application with omics methods opens new avenues in understanding the functioning of plant memory and future plant memory‐based plant ...
Judit Dobránszki, Valya Vassileva, Dolores R. Agius, Panagiotis Nikolaou Moschou, Philippe Gallusci, Margot M.J. Berger, Dóra Farkas, Marcos Fernando Basso, Federico Martinelli   +8 more
wiley   +1 more source

Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease

Journal of Neuropsychology, EarlyView.
Abstract Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD.
Emma Whooley, Vincent Koppelmans, Hayley J. MacDonald, Alison Hall, Marit F. L. Ruitenberg   +4 more
wiley   +1 more source

Evidence that genetic drift not adaptation drives fast‐Z and large‐Z effects in Ficedula flycatchers

Molecular Ecology, EarlyView.
Abstract The sex chromosomes have been hypothesized to play a key role in driving adaptation and speciation across many taxa. The reason for this is thought to be the hemizygosity of the heteromorphic part of sex chromosomes in the heterogametic sex, which exposes recessive mutations to natural and sexual selection. The exposure of recessive beneficial
Madeline A. Chase, Maurine Vilcot, Carina F. Mugal   +2 more
wiley   +1 more source

Specific RNA structures in the 5' untranslated region of the human cytomegalovirus major immediate early transcript are critical for efficient virus replication. [PDF]

mBio
Dickmander B, Hale A, Sanders W, Lenarcic E, Ziehr B, Moorman NJ.   +5 more
europepmc   +1 more source

The Evolution of Locally Adaptive Chromosome Inversions in Mimulus guttatus

Molecular Ecology, EarlyView.
ABSTRACT Chromosomal inversion polymorphisms are ubiquitous across the diversity of diploid organisms and play a significant role in the evolution of adaptations in those species. Inversions are thought to operate as supergenes by trapping adaptive alleles at multiple linked loci through the suppression of recombination. While there is now considerable
Leslie M. Kollar, Lauren E. Stanley, Sunil K. Kenchanmane Raju, David B. Lowry, Chad E. Niederhuth   +4 more
wiley   +1 more source

Genomic Insights Into the Origin, Decline and Recovery of the Once Critically Endangered Iberian Lynx

Molecular Ecology, EarlyView.
ABSTRACT The Iberian lynx was at the brink of extinction by the year 2000 but has since then, and thanks to intensive conservation measures, gone through a remarkable recovery, providing a much‐welcomed and encouraging conservation success story.
José A. Godoy, Enrico Bazzicalupo, Mireia Casas‐Marce, Fernando Cruz, Jesús Fernández, Malin Hasselgren, Daniel Kleinman‐Ruiz, Lorena Lorenzo‐Fernández, María Lucena‐Perez, Elena Marmesat, Begoña Martínez‐Cruz, Lucía Mayor‐Fidalgo, Laia Pérez‐Sorribes, Laura Soriano   +13 more
wiley   +1 more source

The Evolutionary Dynamics of Genetic Mutational Load Throughout Tomato Domestication History

Molecular Ecology, EarlyView.
ABSTRACT Understanding the impact of domestication on deleterious mutations has fascinated evolutionary biologists and breeders alike. A ‘cost of domestication’ has been reported for some organisms through accumulation of gene disruptions or radical amino acid changes.
Hamid Razifard, Sofia Visa, Naama Menda, Lukas Mueller, Denise Tieman, Esther van der Knaap, Ana L. Caicedo   +6 more
wiley   +1 more source

The Flagellin‐Specific Chaperone FliS of Borrelia burgdorferi Controls the Cytoplasmic Pool of Flagellins at the Level of Translation Initiation, Secretion, and Proteolysis

Molecular Microbiology, EarlyView.
FliS, a flagellin protein chaperon of the Lyme disease pathogen Borrelia burgdorferi, controls the cytoplasmic pool of flagellins (FlaB) at the level of translation initiation, secretion, and proteolysis. Deletion of fliS blocks FlaB secretion and translation initiation through a pattern‐switching mechanism of FliS‐FlaB‐FliW/CsrA. Therefore, the mutant
Ching Wooen Sze, Kai Zhang, Michael J. Lynch, Wangbiao Guo, Jun Liu, Brian R. Crane, Chunhao Li   +6 more
wiley   +1 more source

Unravelling the dynamics of seed‐stored mRNAs during seed priming

New Phytologist, EarlyView.
Summary Seed priming is a pre‐sowing treatment that enables more efficient and uniform seed germination; however, it negatively affects seed longevity. In this work, the mRNA dynamics underlying a hydropriming treatment have been investigated. Polysome profiling was performed on seeds during different stages of hydropriming.
Patricija Gran, Tessa W. Visscher, Bing Bai, Harm Nijveen, Amir Mahboubi, Lars L. Bakermans, Leo A. J. Willems, Leónie Bentsink   +7 more
wiley   +1 more source

RNA elements and their biotechnological applications in plants

New Phytologist, EarlyView.
Summary Engineering of plants for improved traits and efficient heterologous protein production can be achieved by modifying or introducing cis‐ or trans‐acting RNA elements. The function of these elements depends not only on their nucleotide sequence but also on their highly dynamic higher order structures.
Filip Lastovka, Hadrien Peyret, George P. Lomonossoff, Betty Y.‐W. Chung   +3 more
wiley   +1 more source