Results 321 to 330 of about 246,994 (340)
Pediatric Dermatology, EarlyView.ABSTRACT Marie Unna hereditary hypotrichosis 1 (MUHH1) is a rare autosomal dominant condition characterized by the absence or scarcity of hair at birth with the growth of coarse, wiry, and unruly hair during childhood and progressive hair loss after puberty.
Sarah Østergaard Holm +5 more
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Revisiting the Evolution and Function of NIP2 Paralogues in the Rhynchosporium Spp. Complex
Plant Pathology, EarlyView.A new long‐read assembly of Rhynchosporium commune reveals ancestral duplication of the Necrosis‐Inducing Protein 2 effector family, which are upregulated during infection but do not cause necrosis on barley. ABSTRACT The fungus Rhynchosporium commune, the causal agent of barley scald disease, contains a paralogous effector gene family called Necrosis ...
Reynaldi Darma +11 more
wiley +1 more source
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Databases of mRNA untranslated regions for metazoa
Computers & Chemistry, 1996The important role that untranslated regions of mRNAs (UTR) may play in gene regulation and expression is now widely accepted. For this reason we developed UTRDB, a specialized database of 5'- and 3'-UTR of eukaryotic mRNAs cleaned of redundancy. This paper describes the composition and the general feature of UTRDB.
Pesole G, Grillo G, Liuni S
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3′untranslated regions: regulation at the end of the road
Current Genetics, 2018Post-transcriptional gene regulation in bacteria plays a major role in the adaptation of bacterial cells to the changing conditions encountered in the environment. In bacteria, most of the regulation at the level of mRNA seems to be targeting the 5'untranslated regions where accessibility to the ribosome-binding site can be modulated to alter gene ...
Youssef El Mouali, Carlos Balsalobre
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How is polyadenylation restricted to 3' untranslated regions?
Yeast, 2023Polyadenylation occurs at numerous sites within 3’ untranslated regions (3’ UTRs) but rarely within coding regions. How does Pol II travel through long coding regions without generating poly(A) sites, yet then permits promiscuous polyadenylation once it reaches the 3’ UTR?
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Regulation by 3′-Untranslated Regions
Annual Review of Genetics, 20173′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside an increased generation of alternative 3′-UTR isoforms. In contrast, the number of coding genes, as well as coding region length, has remained similar. This suggests an important role for 3′
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The composition of untranslated regions in Trypanosoma cruzi genes
Parasitology International, 2009We collected the UTRs from Trypanosomacruzi genes that have been experimentally mapped and are publicly available, and made a comprehensive analysis of their composition features including sequence length, G+C content and relationship to ORF, composition of the most frequent words, and distribution of Simple Sequence Repeats (SSR). T.
Adeilton Brandão, Taijiao Jiang
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The emerging roles of 3′ untranslated regions in cancer
Cancer Letters, 2013Accumulating evidence suggests that 3' untranlated regions (3' UTRs) are critical for spatial and temporal gene expression in both physiological and pathological conditions. The reprogramming of 3' UTRs by various means is a common phenomenon in cancer; disturbances of 3' UTRs significantly increase the risk of cancer susceptibility by acting both in ...
Xin Lu, Jun Li
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The 3′ Untranslated Region of Prohibitin and Cellular Immortalization
Experimental Cell Research, 1996We have been studying the role of the evolutionarily conserved prohibitin gene in cellular immortalization and tumor suppression. Immortalized human cells are classified into four complementation groups (A, B, C, and D) based on the ability of fusion hybrids to become senescent.
R T Dell'Orco +4 more
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Structural and compositional features of untranslated regions of eukaryotic mRNAs
Gene, 1997The important role of 5' and 3' untranslated regions of eukaryotic mRNAs in gene regulation and expression is now widely accepted. In order to study the general structural and compositional features of these sequences we developed UTRdb, a specialized database of 5' and 3'-UTR sequences from seven different taxonomic groups of eukaryotic mRNAs cleaned ...
Pesole G, Liuni S, Grillo G, Saccone C
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