Results 181 to 190 of about 137,203 (272)

Diversity of NKG2C genotypes in a European population: Conserved and recombinant haplotypes in the coding, promoter, and 3'-untranslated regions. [PDF]

HLA, 2022
Asenjo J, Moraru M, Al-Akioui-Sanz K, Altadill M, Muntasell A, López-Botet M, Vilches C.   +6 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Comprehensive mapping of the 5' and 3' untranslated regions of <i>Aspergillus fumigatus</i> reveals diverse mechanisms of mRNA processing including premature transcription termination. [PDF]

RNA
Schrettenbrunner L, Maufrais C, Janbon G, Wallace EWJ, Blango MG.   +4 more
europepmc   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, EarlyView.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Genetic polymorphisms of the 5' untranslated regions of the HSP70 gene in Indonesian cattle populations. [PDF]

Vet World, 2022
Prihandini PW, Primasari A, Aryogi A, Luthfi M, Hariyono DNH.   +4 more
europepmc   +1 more source

5' Untranslated Region SNP [PDF]

, 2020
openaire   +1 more source

MAPK Inhibitor‐Tolerant Persister Cells in Melanoma: Mechanisms and Therapeutic Vulnerabilities

Cancer Science, EarlyView.
Melanoma response to MAPK inhibition progresses from drug‐sensitive cells to drug‐tolerant persister states, which enable survival through adaptive signaling, metabolic rewiring, and phenotypic plasticity. These persister cells serve as an intermediate reservoir from which resistant tumors ultimately emerge. ABSTRACT Though major advancements have been
Bhoomi Shah, Mackenzie M. Mayhew, Jacob Sellers, Russell G. Witt   +3 more
wiley   +1 more source

A new combination of 5'- and 3'-untranslated regions increases the expression of mRNAs in vitro and in vivo. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Antropov DN, Markov OV, Dome AS, Puchkov PA, Shmendel EV, Gladkikh DV, Golyshev VM, Matveeva AM, Maslov MA, Stepanov GA.   +9 more
europepmc   +1 more source

MiR‐375 in CAFs‐Derived EVs Promotes HCC Progression via Regulating RASA1 and May Potentially Serve as a Biomarker for HCC

Cancer Science, EarlyView.
CAFs could transfer EVs miR‐375 into endothelial cells with a low level of RASA1 and further promote EC angiogenesis. Plasma EVs miR‐375 have the potential values as a novel diagnostic and prognostic biomarker for HCC. ABSTRACT Cancer‐associated fibroblasts (CAFs) in the tumor microenvironment play an important role in cancer initiation and progression
Wei Qin, Li Wang, Beiyuan Hu, Cuicui Xiao, XiaoYing Wu, Huan Tian, Songlin Peng   +6 more
wiley   +1 more source

A Luciferase-Based Approach for Functional Screening of 5' and 3' Untranslated Regions of the mRNA Component for mRNA Vaccines. [PDF]

Vaccines (Basel)
Rubtsova M, Mokrushina Y, Andreev D, Poteshnova M, Shepelev N, Koryagina M, Moiseeva E, Malabuiok D, Prokopenko Y, Terekhov S, Chernov A, Vodovozova E, Smirnov I, Dontsova O, Gabibov A, Rubtsov Y.   +15 more
europepmc   +1 more source