Results 81 to 90 of about 837,235 (264)

Characterizations of MV-Algebras Based on the Theory of Falling Shadows

The Scientific World Journal, 2014
Based on the falling shadow theory, the concept of falling fuzzy (implicative) ideals as a generalization of that of a T∧-fuzzy (implicative) ideal is proposed in MV-algebras.
Yongwei Yang, Xiaolong Xin, Pengfei He
doaj   +1 more source

Fuzzy Translations of a Fuzzy Set in UP-Algebras [PDF]

, 2017
In this paper, we apply the concept of fuzzy translations of a fuzzy set to UP-algebras.For any fuzzy set $\mu$ in a UP-algebra,the concepts of fuzzy $\alpha$-translations of $\mu$ of type \textrm{I} and of fuzzy $\beta$-translations of $\mu$ of type ...
Iampan, A. (Aiyared)
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Major Flaws in Conflict Prevention Policies towards Africa. The Conceptual Deficits of International Actors’ Approaches and How to Overcome Them [PDF]

Current thinking on African conflicts suffers from misinterpretations (oversimplification, lack of focus, lack of conceptual clarity, state- centrism and lack of vision).
Andreas Mehler, Hans-Christian Mahnke
core   +3 more sources

A recent exploratory insight on the profile of the innovative entrepreneur: Conclusions from a cross-tabs analysis [PDF]

Despite growing concern towards entrepreneurship, the number of studies directly targeting the profile of the entrepreneur involved in innovative and high-tech new ventures are still scarce.
Isidre March Chorda, Rosa María Yagüe Perales   +1 more
core  

Phase Field Model for Three-Dimensional Dendritic Growth with Fluid Flow

, 2001
We study the effect of fluid flow on three-dimensional (3D) dendrite growth using a phase-field model on an adaptive finite element grid. In order to simulate 3D fluid flow, we use an averaging method for the flow problem coupled to the phase-field ...
A. A. Wheeler, A. Karma, A. N. Brooks, C. Beckermann, D. A. Kessler, D. Kessler, E. Ben-Jacob, J. A. Dantzig, J. Langer, Jonathan A. Dantzig, Jun-Ho Jeong, L. V. Kale, M. Bhandarkar, N. Provatas, N. Provatas, Nigel Goldenfeld, P. Bouissou, P. M. Gresho, S. Chen, S. H. Davis, W. W. Mullins, X. Mikic, Y.-T. Kim, Y.-W. Lee   +23 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source