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A DNA/Upconversion Nanoparticle Complex Enables Controlled Co‐Delivery of CRISPR‐Cas9 and Photodynamic Agents for Synergistic Cancer Therapy

Advanced Materials
Photodynamic therapy (PDT) depends on the light‐irradiated exciting of photosensitizer (PS) to generate reactive oxygen species (ROS), which faces challenges and limitations in hypoxia and antioxidant response of cancer cells, and limited tissue ...
Xiaocui Guo, Fan Li, Peifeng Liu
exaly   +2 more sources

Upconversion Nanoparticle-Mediated Optogenetics.

Advances in Experimental Medicine and Biology, 2021
Upconversion nanoparticle-mediated optogenetics enables remote delivery of upconverted visible light from a near-infrared light source to targeted neurons or areas, with the precision of a pulse of laser light in vivo for effective deep-tissue neuromodulation.
Zhigao Yi, A. All, Xiaogang Liu
semanticscholar   +3 more sources

Understanding FRET in Upconversion Nanoparticle Nucleic Acid Biosensors.

Nano letters (Print), 2023
Upconversion nanoparticles (UCNPs) have been frequently applied in Förster resonance energy transfer (FRET) bioanalysis. However, the understanding of how surface coatings, bioconjugation, and dye-surface distance influence FRET biosensing performance ...
S. Bhuckory   +6 more
semanticscholar   +1 more source

Upconversion nanoparticle-based optogenetic nanosystem for photodynamic therapy and cascade gene therapy.

Acta Biomaterialia, 2022
Most photosensitizer molecules used for the photodynamic therapy (PDT) are chemically-synthesized organic photosensitizer dyes which show several limitations such as unsatisfactory cell uptake, weak selectivity and off-target phototoxicity.
Xinyue Song   +7 more
semanticscholar   +1 more source

A reliable upconversion nanoparticle-based immunochromatographic assay for the highly sensitive determination of olaquindox in fish muscle and water samples.

Food Chemistry, 2022
Olaquindox residues in food from its illegal use has received great attention. Here, an immunoassay strategy integrating an upconversion nanoparticle (UCNP)-based immunochromatographic strip with a fluorescence reader was proposed for the highly ...
Z. Wen   +8 more
semanticscholar   +1 more source

Upconversion Nanoparticle-Integrated Bilayer Inverse Opal Photonic Crystal Film for the Triple Anticounterfeiting.

ACS Applied Materials and Interfaces, 2022
Optical anticounterfeiting plays a vital role in information security because it can be recognized by the naked eye and is difficult to imitate. Herein, a hydrophilic modified upconversion nanoparticle (M-UCNP)-integrated bilayer inverse opal photonic ...
Zhipeng Meng   +5 more
semanticscholar   +1 more source

Responsive Sensors of Upconversion Nanoparticles

ACS Sensors, 2021
Upconversion nanoparticles are a class of luminescent materials that convert longer-wavelength near-infrared photons into visible and ultraviolet emissions. They can respond to various external stimuli, which underpins many opportunities for developing the next generation of sensing technologies.
Gungun Lin, Dayong Jin
openaire   +2 more sources

Near-Infrared Light and Upconversion Nanoparticle Defined Nitric Oxide-Based Osteoporosis Targeting Therapy.

ACS Nano, 2021
Osteoporosis is one of the most common diseases affecting bone metabolism. Nitric oxide (NO), an endogenous gas molecule involved in osteogenesis, can effectively promote the proliferation and differentiation of osteoblasts.
Jing Ye   +9 more
semanticscholar   +1 more source

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