Results 41 to 50 of about 274,718 (313)
The Clinical Respiratory Journal, 2009 AbstractBackground and aims: Bronchiectasis is defined as an abnormal and irreversible dilatation of the bronchi, often associated with chronic productive cough, airway obstruction, and recurrent infections.Methods: MEDLINE data from 1978 to November 2008 was analysed.
M. Pappalettera +5 more
openaire +3 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Update games and update networks
Journal of Discrete Algorithms, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Michael J. Dinneen, Bakhadyr Khoussainov
openaire +1 more source
Latest Advances in Finite Element Modelling and Model Updating of Cable-Stayed Bridges [PDF]
, 2022 As important links in the transport infrastructure system, cable-stayed bridges are among the most popular candidates for implementing structural health monitoring (SHM) technology.
Guan, Hong +9 more
core +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Paracoccidioidomycosis: an update [PDF]
Clinical Microbiology Reviews, 1993 This review summarizes knowledge on various aspects of paracoccidioidomycosis. Mycelial propagules, chlamydospores, and arthroconidia exhibit thermal dimorphism; arthroconidia are infectious in animals and, by electron microscopy, appear well provided for survival. The mycelial-to-yeast-phase transformation requires a strict control of glucan synthesis
Brummer, Elmer +2 more
openaire +3 more sources
Автоматизация технологических и бизнес-процессов, 2017 The content, meaning and methodological possibilities of use of the developed and proposed balance of technological efficiency of operation of a technical object are considered. The methodological basis for offset in different conditions and modes of use
S. Voinova
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Updating the regulatory framework for the design and construction of water supply and sanitation systems [PDF]
BIO Web of ConferencesThe paper discusses the aspects of updating and approaches to improving the regulatory and technical documents, i.e. Codes of Practice (CPs), State Standards (GOSTs) to enhance the efficiency of design, construction and operation of water supply and ...
Primin Oleg
doaj +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source