Results 91 to 100 of about 547,836 (276)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
MOODLE MANUAL UPGRADE METHODOLOGY
This abstract outlines a systematic four-step methodology for upgrading Moodle from version 3.6.5 to 3.9.9. The process begins with comprehensive backup and preparation, followed by the replacement of the Moodle codebase and execution of the upgrade ...
S. S. Atanasov
doaj +1 more source
Gains from the upgrade of the cold neutron triple-axis spectrometer FLEXX at the BER-II reactor
The upgrade of the cold neutron triple-axis spectrometer FLEXX is described. We discuss the characterisation of the gains from the new primary spectrometer, including a larger guide and double focussing monochromator, and present measurements of the ...
Groitl, F. +6 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Triple GEM Detectors for the Forward Tracker in STAR
Future measurements of the flavor-separated spin structure of the proton via parity-violating W boson production at RHIC require an upgrade of the forward tracking system of the STAR detector. This upgrade will allow the reconstruction of the charge sign
Kelsey, James +9 more
core +1 more source
While the current interferometric gravitational wave detectors are approching their nominal sensitivity, the new generation of detectors is in an advanced design phase. The Virgo collaboration is de.ning now the path to arrive to a complete design of the advanced version of the detector within about two years.
F. ACERNESE +121 more
openaire +5 more sources
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Minimum Storage Regenerating Codes for Scalable Distributed Storage
Regenerating codes (RGCs) have recently been proposed to reduce the repair traffic of ( $n,k$ ) erasure-coded distributed storage systems. Moreover, RGCs can also be used in a scalable distributed storage scenario where $n$ is increased (decreased) to ...
Huayu Zhang +4 more
doaj +1 more source
This project is a racing and car collecting video game, which can be played by one or more players. A player can buy cars, upgrade owned cars, tune owned cars, and use owned cars to race for money to buy, upgrade, and tune cars.
Chen, Yangsilong, Vu, Thien C.
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source

