Results 131 to 140 of about 547,836 (276)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Upgrading hypertension treatment [PDF]
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2020 Goetze, Jens P. +3 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
The impact of trade liberalization on skill upgrading. Evidence from Argentina [PDF]
In this paper I study the effects of a regional free trade agreement on the demand for skill. I start by documenting a series of facts to shed light on the determinants of a steep increase in the relative demand of skilled labor in a panel of Argentinean
Paula Bustos
core
Upgrading: surviving a Voyager 7 upgrade
, 2007 Presentation delivered at the February, 2011 Ex Libris Southwest User Group meeting.
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Innovations in implantation techniques of ventricular assist devicesCentral Message
JTCVS Open, 2021 Jasmin S. Hanke, MD +4 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Status of the HIE-ISOLDE project at CERN
, 2017 The HIE-ISOLDE project represents a major upgrade of the ISOLDE nuclear facility with a mandate to significantly improve the quality and increase the intensity and energy of radioactive nuclear beams produced at CERN.
Bernardes, A. P. +13 more
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