Results 131 to 140 of about 107,473 (289)

Feature Disentangling and Combination Implemented by Spin–Orbit Torque Magnetic Tunnel Junctions

open access: yesAdvanced Intelligent Systems, EarlyView.
Spin–orbit torque magnetic tunnel junctions (SOT‐MTJs) enable efficient feature disentangling and integration in image data. A proposed algorithm leverages SOT‐MTJs as true random number generators to disentangle and recombine features in real time, with experimental validation on emoji and facial datasets.
Xiaohan Li   +15 more
wiley   +1 more source

Programmable‐Stiffness Tensegrity Continuum Robot for Adaptive Multicurvature On‐Orbit Assembly

open access: yesAdvanced Intelligent Systems, EarlyView.
A bioinspired tensegrity‐based continuum robot (BTCR) with programmable stiffness enables adaptive multicurvature morphing via coordinated intra‐ and intermodule regulation. A unified energy‐based framework predicts self‐equilibrium and deformation for serial modules. Experiments and Simulations demonstrate reconfiguration into hexagonal, circular, and
Yubin Wu   +5 more
wiley   +1 more source

Direct Selection of Functional De Novo Macrocycles for Activation of On‐Cellulo Insulin Receptor

open access: yesAngewandte Chemie, EarlyView.
A live‐cell screening platform, RaPID‐ExCells, integrates mRNA display‐derived macrocyclic peptide libraries with functional selection against native cell‐surface receptors. Application to the insulin receptor enabled de novo discovery of a macrocyclic agonist that activates endogenous signaling despite weak in vitro binding, highlighting the power of ...
Yun‐Hsuan Kuo   +3 more
wiley   +2 more sources

Rapid Genome and Exome Sequencing in Inpatients: Clinical Impact at a Tertiary Academic Medical Center

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The objective of this study is to describe outcomes of rapid exome (rES) and rapid genome sequencing (rGS) in an inpatient setting. This is a retrospective cohort of inpatients with rES or rGS during their hospitalization between April 2016 and November 2023.
Cecilia M. Kessler   +5 more
wiley   +1 more source

Depolymerization and Reuse of Polycarbonates: Emerging Classes, Mechanisms and Challenges

open access: yesAngewandte Chemie, EarlyView.
This review collects the latest developments in the area of chemical and catalytic polycarbonate recycling strategies and includes the controlled degradation of similar types of macromolecules. Apart from the main strategies for deconstruction, the key mechanistic features of these depolymerization processes are also discussed together with the ...
Davide Rigo   +4 more
wiley   +2 more sources

KDM2B‐Related Neurodevelopmental Disorder A Case‐Series Supporting the CxxC Domain Phenotype With Emphasis on Ocular and Dermatologic Features

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The KDM2B‐related neurodevelopmental disorder is a recently identified Mendelian disorder of the epigenetic machinery associated with pathogenic variants in KDM2B. Global developmental delay, intellectual disability, congenital anomalies, and systemic manifestations characterize the disorder.
Adriana Gomes   +3 more
wiley   +1 more source

Ligand‐Intercalated MOFs Enable Reaction‐Pathway Engineering in Biomass Electrooxidation via Steric and π‐Electronic Microenvironment Control

open access: yesAngewandte Chemie, EarlyView.
Through ligand length and π‐electron density modulation, metal–organic frameworks (MOFs) improve mass transport and hydrogen atom transfer (HAT), thus improving biomass electrooxidation. ABSTRACT Controlling reaction pathways in electrocatalytic biomass upgrading remains challenging because mass transport, substrate adsorption, and elementary kinetics ...
Junjie Chen   +12 more
wiley   +2 more sources

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt   +9 more
wiley   +1 more source

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