Results 181 to 190 of about 82,838 (255)

Unveiling the metabolic profile and anti-inflammatory potential of apple of Sodom (Calotropis procera (Aiton) W.T.) by UPLC-MS/MS chemometric analysis. [PDF]

Sci Rep
El-Banna AA, Ibrahim RS, Ghareeb DA, Nassief SM.   +3 more
europepmc   +1 more source

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

iMetaMed, EarlyView.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang, Zhen Ma, Yang Li, Shaoli Wang, Yanjiao Zhang, Lei Song, Xianyu Li, Zhen Liu   +7 more
wiley   +1 more source

Validation of a UPLC-MS/MS Method for Quantifying Intracellular Olaparib Levels in Resistant Ovarian Cancer Cells. [PDF]

Pharmaceuticals (Basel)
Kmiecik SW, Lewis J, Schwickert J, Breitenreicher H, Sprick MR, Burhenne J.   +5 more
europepmc   +1 more source

A synthetic community promotes macadamia growth via root‐microbe interactions and systemic plant responses

iMetaOmics, EarlyView.
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao, Qiumei Liu, Wenlin Wang, Qiujin Tan, Chunheng Zhou, Dejun Li   +5 more
wiley   +1 more source

Determination of metabolite differences between loquat nectar and honey by UPLC-MS/MS. [PDF]

PeerJ
Sun X, Shu R, Qu Y, Dai J.
europepmc   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

UPLC-MS/MS analysis and bioactivity comparison of wild and cultivated <i>Taihangia rupestris</i> leaves: antioxidant and α-glucosidase inhibitory activities with active compound screening. [PDF]

RSC Adv
Yin JT, Wang DM, Wu XC, Lu J, Qian ZM, Li DQ, Feng R.   +6 more
europepmc   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Effective extraction and determination of 9 β-lactams in water and milk samples by a novel magnetic covalent organic framework combined with UPLC-MS/MS. [PDF]

RSC Adv
Li L, Li N, Niu W, Guo A, Ma L, Zhao W, Zhang Y, Wang K.   +7 more
europepmc   +1 more source

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner, Jack K. Dziubek, Nicole A. Joseph, Sarah E. Chapman, Tori J. Chace, Dongxiao Sun, Zachary T. Bitzer, Antoine Stier, Robert A. Mauck, Patricia L. Jones, Mark F. Haussmann   +10 more
wiley   +1 more source