Results 81 to 90 of about 2,172,385 (299)
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
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HeliyonSelecting the best power source that is legal, affordable, environmentally friendly, and able to ensure long-term viability is a difficult but vital task.
Muhammad Abdullah +3 more
doaj +1 more source
The Lower And Upper Approximations In A Group
, 2012 In this paper, we generalize some propositions in [C.Z. Wang, D.G. Chen, A short note on some properties of rough groups, Comput. Math. Appl. 59(2010)431-436.] and we give some equivalent conditions for rough subgroups. The notion of minimal upper rough subgroups is introduced and a equivalent characterization is given, which implies the rough version ...
Zhaohao Wang, Lan Shu
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Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Approximating Upper Degree-Constrained Partial Orientations
CoRR, 2014 In the Upper Degree-Constrained Partial Orientation problem we are given an undirected graph $G=(V,E)$, together with two degree constraint functions $d^-,d^+ : V \to \mathbb{N}$. The goal is to orient as many edges as possible, in such a way that for each vertex $v \in V$ the number of arcs entering $v$ is at most $d^-(v)$, whereas the number of arcs ...
Marek Cygan, Tomasz Kociumaka
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Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Upper Iowa University Catalog; Upper Iowa University Bulletin
[Title], Upper Iowa University Digital Archives, [Reference URL]. See 'About' page for more information;Digitized 600 dpi 48-bit color tiff, saved as jpeg, edited with Windows Live Photo ...
Upper Iowa University
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View from the bluff to south-west, three-fourths of a mile distant
, 1887 Drawing of the Upper Iowa University campus showing the Church [now Parker-Fox], North Hall [no longer exists], Main Building [now Alexander-Dickman], and South Hall [no longer exists][Title], Upper Iowa University Digital Archives, [Reference URL]. See
Upper Iowa University
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Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
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Mean-field approximation of stochastic population processes in games [PDF]
We here establish an upper bound on the probability for deviations of a Markov population process from its mean-field approximation.
Jörgen Weibull, Michel Benaïm
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