Results 111 to 120 of about 4,152,384 (323)
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Upper bounds for 21st-century surface air temperatures in the Western United States
Environmental Research LettersThe last decade has seen a large number of severe heatwaves that were unprecedented in the observational record, highlighting challenges associated with observationally-based statistical quantification of the likelihood and magnitude of future extreme ...
Mark D Risser +3 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Upper-Bound Performance of a Wide-Band Adaptive Modem
, 1999 Adaptive modulation is applied in conjunction with a decision-feedback equalizer (DFE) in order to mitigate the effects of the slowly varying wide-band multipath Rayleigh fading channel in a noise-limited environment.
Wong, C.H., Hanzo, L.
core
Robust Stability Analysis for a Perturbed Single-Area Power System Model
Cybernetics and Information Technologies, 2015 This research work investigates the derivation of a fixed upper matrix bound for the solution of one class of parameter-dependent Continuous Algebraic Lyapunov Equations (CALE).
Savov Svetoslav, Popchev Ivan
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Upper-Bound Performance of a Wide-Band Adaptive Modem
, 2000 Adaptive modulation is applied in conjunction with a decision-feedback equalizer (DFE) in order to mitigate the effects of the slowly varying wide-band multipath Rayleigh fading channel in a noise-limited environment.
Wong, C.H., Hanzo, L.
core
Communications Earth & EnvironmentDepleted oil and gas reservoirs provide an opportunity to repurpose underperforming wells and reuse existing subsurface infrastructure to support Net Zero transitions.
Nikhil S. Rajput +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source