Results 21 to 30 of about 198,408 (356)

A phase 1b study of venetoclax and azacitidine combination in patients with relapsed or refractory myelodysplastic syndromes

American Journal of Hematology, Volume 98, Issue 2, Page 272-281, February 2023., 2023
Abstract Patients with relapsed/refractory (R/R) higher‐risk myelodysplastic syndromes (MDS) have a dismal median overall survival (OS) after failing hypomethylating agent (HMA) treatment. There is no standard of care for patients after HMA therapy failure; hence, there is a critical need for effective therapeutic strategies.
Amer M. Zeidan, Uma Borate, Daniel A. Pollyea, Andrew M. Brunner, Fernando Roncolato, Jacqueline S. Garcia, Robin Filshie, Olatoyosi Odenike, Anne Marie Watson, Ravitharan Krishnadasan, Ashish Bajel, Kiran Naqvi, Jiuhong Zha, Wei‐Han Cheng, Ying Zhou, David Hoffman, Jason G. Harb, Jalaja Potluri, Guillermo Garcia‐Manero   +18 more
wiley   +1 more source

Risk of upper gastrointestinal bleeding in patients on oral anticoagulant and proton pump inhibitor co-therapy.

PLoS ONE, 2021
BackgroundProton pump inhibitors (PPIs) are known to reduce the risk of upper gastrointestinal bleeding in patients on oral anticoagulants, and patients are increasingly on oral anticoagulants and PPI co-therapy.
Hyun-Jung Lee, Hyung-Kwan Kim, Bong-Sung Kim, Kyung-Do Han, Jun-Bean Park, Heesun Lee, Seung-Pyo Lee, Yong-Jin Kim   +7 more
doaj   +1 more source

Assesment of Upper Gastrointestinal Bleeding in the Pediatric Emergency Department

Journal of Pediatric Emergency and Intensive Care Medicine, 2023
Introduction:Upper gastrointestinal bleeding is an important emergency problem that can occur at any age in childhood and requires urgent treatment for the underlying cause.
Aysun Tekeli, Gülseren Şahin, Betül Öztürk, Ferda Özbay Hoşnut, İlknur Bodur, Ayla Akca Çağlar, Can Demir Karacan, Nilden Tuygun   +7 more
doaj   +1 more source

Viruses in sanctuary chimpanzees across Africa

American Journal of Primatology, Volume 85, Issue 1, January 2023., 2023
Abstract Infectious disease is a major concern for both wild and captive primate populations. Primate sanctuaries in Africa provide critical protection to thousands of wild‐born, orphan primates confiscated from the bushmeat and pet trades. However, uncertainty about the infectious agents these individuals potentially harbor has important implications ...
Emily Dunay, Leah A. Owens, Christopher D. Dunn, Joshua Rukundo, Rebeca Atencia, Megan F. Cole, Averill Cantwell, Melissa Emery Thompson, Alexandra G. Rosati, Tony L. Goldberg   +9 more
wiley   +1 more source

Non-Variceal Upper Gastrointestinal Bleeding [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Non-variceal upper gastrointestinal bleeding (NVUGIB), which predominantly occurs secondary to peptic ulcers, presents a major challenge in emergency departments and is associated with high mortality rates.
Dong Jin Yoon, Joon Sung Kim
doaj   +1 more source

A Fibreoptic Endoscopic Study of Upper Gastrointestinal Bleeding at Bugando Medical Centre in Northwestern Tanzania: a Retrospective Review of 240 Cases. [PDF]

, 2012
Upper gastrointestinal (GI) bleeding is recognized as a common and potentially life-threatening abdominal emergency that needs a prompt assessment and aggressive emergency treatment.
A Elghuel, A Timraz, AB Olokoba, AG Kankaria, Anthony Liwa, C Meaden, C Zaltman, D Pateron, DA Peura, DE Elliott, DJ Cook, DJ Exon, Eliasa Mkongo, EM Vreeburg, FK Chan, G Theocharis, GS Kibiki, HC Wolfsen, HM Salih, Hyasinta Jaka, J Chasawat, J Villanueva Palacios, JA Forrest, K Aoki, K Kivkin, K Palmer, M Suba, M Urassa, Mabula D Mchembe, Mariam Mirambo, ME Van Leerdam, Mheta Koy, MJ Kaviani, MN Lakhwani, N Sarin, NK Arora, P Vlavianos, Phillipo L Chalya, Rodrick Kabangila, S Mustapha, SA Hearnshaw, T Alempijevic, TA Rockall, TA Rockall, V Balderas, Wolfgang Scheppach   +45 more
core   +2 more sources

A cerebrovascular stroke following endoscopy for an elderly patient with acute upper gastrointestinal bleeding

Alexandria Journal of Medicine, 2016
Elderly people constitute an increasing proportion of those presenting with acute upper gastrointestinal bleeding. Not only in upper gastrointestinal bleeding is advanced age a risk of death, but also exceeding 60 years of age results in an increased ...
Ahmed Gado, Basel Ebeid
doaj   +1 more source

The Causes of Upper Gastrointestinal Bleeding in the National Referral Hospital: Evaluation on Upper Gastrointestinal Tract Endoscopic Result in Five Years Period [PDF]

, 2005
Backgrounds: Gastrointestinal bleeding such as hematemesis or melena are common conditions in clinical practice and endoscopic service. The mortality rate due to gastrointestinal bleeding is relatively high.
Abdullah, M. (Murdani), Daldiyono, D. (Daldiyono), Djojoningrat, D. (Dharmika), Makmun, D. (Dadang), Manan, C. (Chudahman), Rani, A. A. (Abdul), Simadibrata, M. (Marcellus), Syam, A. F. (Ari)   +7 more
core   +1 more source

Low-dose aspirin and risk of upper/lower gastrointestinal bleeding by bleed severity: a cohort study with nested case-control analysis using primary care electronic health records from the United Kingdom

Annals of Medicine, 2019
Introduction Risks of low-dose aspirin-associated upper and lower gastrointestinal bleeds (UGIB/LGIB) may vary by severity and presence of cardiovascular disease (CVD).
Luis A. García Rodríguez, Angel Lanas, Montse Soriano-Gabarró, Lucía Cea Soriano   +3 more
doaj   +1 more source

Antiplatelet agents and/or anticoagulants are not associated with worse outcome following nonvariceal upper gastrointestinal bleeding [PDF]

, 2016
BACKGROUND: Nonvariceal upper gastrointestinal bleeding emerges as a major complication of using antiplatelet agents and/or anticoagulants and represents a clinical challenge in patients undergoing these therapies.
Dinis-Ribeiro, M., Maia, L., Marcos-Pinto, R., Pedroto, I., Salgueiro, P., Teles-Sampaio, E.   +5 more
core   +1 more source