Results 271 to 280 of about 104,519 (307)

Impact of Evolving Evidence on Pharmacological Therapy for Alcohol‐Associated Hepatitis in Alberta: A Population‐Based Study of Practice Trends and MELD‐Stratified Effectiveness of Corticosteroids

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this population‐based study in Alberta, Canada, evidence from RCTs led to a rapid reversal in pentoxifylline use, prior to formal guideline updates. Real‐world data support a modest short‐term benefit of CS and illustrate the potential of target trial emulation to assess treatment effectiveness in specific groups of patients. ABSTRACT Background and
Abdel‐Aziz Shaheen   +3 more
wiley   +1 more source

Factors associated with flexible cystoscope longevity: an analysis of supplier and health service datasets

open access: yesBJU International, EarlyView.
Objectives To investigate the associations between how reusable flexible cystoscopes (FCs) are managed during their functioning lifetime and their longevity. Patients and Methods This was an exploratory retrospective analysis of administrative data collected by a medical supplies company (KARL STORZ Endoscopy (UK) Ltd) on FC usage linked at a National ...
Joseph B. John   +5 more
wiley   +1 more source

Development and Validation of a Urinary Exosomal miRNA Diagnostic Panel for Early Detection of Esophageal Cancer

open access: yesCancer Science, EarlyView.
Using a machine learning–based approach in a multi‐institutional prospective cohort, we identified a robust miRNA signature that demonstrated high diagnostic accuracy for esophageal squamous cell carcinoma. Our 57‐miRNA panel achieved an AUC of 0.90 in the proof‐of‐concept cohort and 0.85 in an independent validation cohort, with a sensitivity of 84 ...
Tatsuro Murano   +14 more
wiley   +1 more source

Experts' Perceptions Regarding Testing for Helicobacter pylori Infection During Upper Gastrointestinal Endoscopy and Subsequent Eradication Therapy. [PDF]

open access: yesKorean J Helicobacter Up Gastrointest Res
Kim I   +10 more
europepmc   +1 more source

Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency

open access: yesClinical Genetics, EarlyView.
We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou   +3 more
wiley   +1 more source

Peritoneal Sarcoidosis

open access: yes
ANZ Journal of Surgery, EarlyView.
Luiz Eduardo Correia Miranda   +2 more
wiley   +1 more source

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