Results 11 to 20 of about 304,575 (302)

Targeting CLDN18.2 in cancers of the gastrointestinal tract: New drugs and new indications

Frontiers in Oncology, 2023
Cancers of the gastrointestinal (GI) tract greatly contribute to the global cancer burden and cancer-related death. Claudin-18.2(CLDN18.2), a transmembrane protein, is a major component of tight junctions and plays an important role in the maintenance of
Jinxia Chen, Zhiyuan Xu, Zhiyuan Xu, Zhiyuan Xu, Can Hu, Can Hu, Can Hu, Shengjie Zhang, Shengjie Zhang, Shengjie Zhang, Mengli Zi, Li Yuan, Li Yuan, Li Yuan, Xiangdong Cheng, Xiangdong Cheng, Xiangdong Cheng   +16 more
doaj   +1 more source

The role of macrophages in gastric cancer

Frontiers in Immunology, 2023
As one of the deadliest cancers of the gastrointestinal tract, there has been limited improvement in long-term survival rates for gastric cancer (GC) in recent decades.
Jiaqing Zhang, Jiaqing Zhang, Can Hu, Can Hu, Can Hu, Ruolan Zhang, Ruolan Zhang, Jingli Xu, Jingli Xu, Yanqiang Zhang, Yanqiang Zhang, Yanqiang Zhang, Li Yuan, Li Yuan, Li Yuan, Shengjie Zhang, Shengjie Zhang, Shengjie Zhang, Siwei Pan, Siwei Pan, Siwei Pan, Mengxuan Cao, Mengxuan Cao, Mengxuan Cao, Jiangjiang Qin, Jiangjiang Qin, Jiangjiang Qin, Xiangdong Cheng, Xiangdong Cheng, Xiangdong Cheng, Zhiyuan Xu, Zhiyuan Xu, Zhiyuan Xu   +32 more
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Role of linked color imaging for upper gastrointestinal disease: present and future [PDF]

Clinical Endoscopy, 2023
Techniques for upper gastrointestinal endoscopy are advancing to facilitate lesion detection and improve prognosis. However, most early tumors in the upper gastrointestinal tract exhibit subtle color changes or morphological features that are difficult ...
Sang Pyo Lee
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Critical Competences for the Management of Post-Operative Course in Patients with Digestive Tract Cancer: The Contribution of MADIT Methodology for a Nine-Month Longitudinal Study

Behavioral Sciences, 2022
There is a high postoperative morbidity rate after cancer surgery, that impairs patients’ self-management, job condition and economic strength. This paper describes the results of a peculiar psychological intervention on patients undergoing surgery for ...
Eleonora Pinto, Alessandro Fabbian, Rita Alfieri, Anna Da Roit, Salvatore Marano, Genny Mattara, Pierluigi Pilati, Carlo Castoro, Marco Cavarzan, Marta Silvia Dalla Riva, Luisa Orrù, Gian Piero Turchi   +11 more
doaj   +1 more source

Gastrointestinal stromal tumor (GIST) of the Treitz’s angle– a very rare cause of high bowel obstruction [PDF]

, 2016
Gastrointestinal stromal tumors (GIST) are somewhat rare gastrointestinal tumors - approximately 1% to 3% incidence, but they are the most common mesenchymal neoplasms of the gastrointestinal tract.
Georgescu, Lota Corina, Pătraşcu, Traian, Tobă, Mădălina Elena, Ungureanu, Dan Florin   +3 more
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Impact of Environmental and Pharmacologic Changes on the Upper Gastrointestinal Microbiome

Biomedicines, 2021
Diseases of the upper gastrointestinal tract have become more prevalent over time. Mechanisms of disease formation are still only partially understood.
Joshua Bilello, Ikenna Okereke
doaj   +1 more source

Managing the Consequences of Oncological Major Surgery: A Short- and Medium-Term Skills Assessment Proposal for Patient and Caregiver through M.A.D.I.T. Methodology

Behavioral Sciences, 2022
The effects of cancer surgery and treatment harm patients’ life and working ability: major causes of this can be intensified by the postoperative symptoms.
Gian Piero Turchi, Alessandro Fabbian, Rita Alfieri, Anna Da Roit, Salvatore Marano, Genny Mattara, Pierluigi Pilati, Carlo Castoro, Davide Bassi, Marta Silvia Dalla Riva, Luisa Orrù, Eleonora Pinto   +11 more
doaj   +1 more source

Endoscopic findings and psychometric abnormalities: what is the relationship in upper endoscopic outpatients? [PDF]

, 2015
Background. Psychological disorders are often associated with diseases of the upper digestive tract. Although emotions can influence gastrointestinal function in healthy individuals, psychological setting in upper gastrointestinal patients are unclear ...
ANGELINI, Rita, FILIPPINI, Angelo, MARIANETTI, Massimo, MINA, Concetta, PETRARCA, LAURA, PONTONE, Paolo, PONTONE, Stefano, RIDOLA, LORENZO, STANDOLI, MONICA   +8 more
core   +1 more source

Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine [PDF]

, 2019
Background: The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake.
Bogatyrev, Said R., Ismagilov, Rustem F., Rolando, Justin C.   +2 more
core   +1 more source

Claudin18.2 as a potential therapeutic target for primary ovarian mucinous carcinomas and metastatic ovarian mucinous carcinomas from upper gastrointestinal primary tumours

BMC Cancer, 2023
Background The vast majority of ovarian mucinous carcinomas are metastatic tumours derived from nonovarian primary cancers, typically gastrointestinal neoplasms.
Fujun Wang, Yao Yang, Xiuzhen Du, Xiaoying Zhu, Yanjiao Hu, Changyu Lu, Lei Sui, Han Zhao, Kejuan Song, Qin Yao   +9 more
doaj   +1 more source