Results 101 to 110 of about 9,149,520 (280)

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Study of inaccuracy measures of record values [PDF]

In this paper, we investigate inaccuracy measures based on record values, focusing on the relationship between the distribution of the n-th upper and lower k-record values and the parent distribution.
Gupta, Nitin, Chaudhary, Santosh Kumar
core   +1 more source

One- and two-sided prediction intervals for future Pareto record values with applications

Journal of Statistical Theory and Applications (JSTA)
Based on upper record values in a series of observations over time from a Pareto distribution, an exact and several approximate one-sided and two-sided prediction intervals for the next record value (or for another future record value) to appear are ...
Anja B. Schmiedt, Christina Empacher, Udo Kamps   +2 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Upper Thames River Conservation Authority, Clean Up Rural Beaches (CURB) Implementation Program 1995/96 final report [PDF]

, 1996
1995 marked the Upper Thames River Conservation Authority's (UTRCA) fifth and final year of involvement in the Clean Up Rural Beaches (CURB) Program.
Upper Thames River Conservation Authority
core   +1 more source

Properties of Residual Cumulative Sharma–Taneja–Mittal Model and Its Extensions in Reliability Theory with Applications to Human Health Analysis and Mixed Coherent Mechanisms

Entropy
The entropy measure of residual cumulative Sharma–Taneja–Mittal is an alternative measure of uncertainty for residual cumulative entropy. This study investigates further theoretical properties and develops nonparametric estimation procedures for the ...
Mohamed Said Mohamed, Hanan H. Sakr
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Bayesian and empirical-Bayesian evaluations of the Topp–Leone lifetime model using lower record statistics

AIP Advances
Record statistics are generally used to measure a process’ stochastic behavior at previously unheard-of values, either upper or lower. It can be obtained or calculated using order statistics from a sample whose size is dictated by the values and order of
Ohud A. Alqasem, Heba S. Mohammed, Ahmed Elshahhat, H. A. Hussein, Z. F. Jaheen   +4 more
doaj   +1 more source

Breaking Ageing Records

Nordic Yearbook of Population Research
This study explores subnational population ageing across Denmark, Finland, Iceland, Norway, and Sweden by examining municipalities that hold record values in three ageing measures: the share of the population aged 65 and over, mean age, and the ...
Sebastian Hanika
doaj   +1 more source