Results 101 to 110 of about 2,799,641 (305)

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source

The effect of profiling report on antibiotic prescription for upper respiratory tract infection [PDF]

, 2013
Introduction: Upper respiratory tract infection (URTI) is a common encounter in primary care and mostly viral in origin. Despite frequent reminders to primary care providers on judicious use of antibiotics for URTI, the practice is still rampant. Methods:
Mohd Fozi K, Kamaliah MN
core  

Molecular epidemiology of human rhinovirus infections in Kilifi, coastal Kenya [PDF]

, 2012
This study reports pediatric surveillance over 3 years for human rhinovirus (HRV) at the District Hospital of Kilifi, coastal Kenya. Nasopharyngeal samples were collected from children presenting at outpatient clinic with no signs of acute respiratory ...
Onyango, Clayton O., Agoti, Charles N., Bett, Ann, Cane, Patricia, Nokes, D. James, Munywoki, Patrick K., Welch, Stephen R., Ngama, Mwanajuma, Myers, Richard   +8 more
core   +1 more source

The microbiome of the upper respiratory tract in health and disease

BMC Biology, 2019
The human upper respiratory tract (URT) offers a variety of niches for microbial colonization. Local microbial communities are shaped by the different characteristics of the specific location within the URT, but also by the interaction with both external
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf, Christine Moissl-Eichinger   +3 more
doaj   +1 more source

The Infections of the Upper Respiratory Tract in Children

International Journal of Immunopathology and Pharmacology, 2010
Upper respiratory tract infections in children are common and usually self-limiting conditions, which include acute otitis media (AOM), acute rhinosinusitis (ARS), and acute pharyngitis (AP). Management of pediatric AOM considers observation strategy for selected and uncomplicated cases, older than 2 years of age, only when adequate follow-up can be ...
BONSIGNORI F, CHIAPPINI, ELENA, DE MARTINO, MAURIZIO   +2 more
openaire   +3 more sources

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber, Manuel Lasch, Veronika Volgger, Clemens Stihl, Philipp Teupe, Fabienne Oettgen, Sophia Gantner, Moritz Gröger   +7 more
wiley   +1 more source

Influence of a Montmorency cherry juice blend on indices of exercise-induced stress and upper respiratory tract symptoms following marathon running - A pilot investigation. [PDF]

, 2015
This is the first study that provides encouraging evidence of the potential role of Montmorency cherries in reducing the development of URTS post-Marathon possibly caused by exercise-induced hyperventilation trauma, and/or other infectious and non ...
Hill, Jessica A., Jessica A Hill, McHugh, Malachy, Dimitriou, L., Jehnali, Ahmed, Lygeri Dimitriou, Glyn Howatson, Jehnali, A., Ahmed Jehnali, Brouner, James, Jenhali, Ahmed, Dunbar, J., Dimitriou, Lygeri, Joe Dunbar, McHugh, M. P., Howatson, Glyn, James Brouner, Hill, Jessica, Hill, J. A., Howatson, G., Brouner, J., Dunbar, Joe, McHugh, Malachy P., Malachy P. McHugh, McHugh, M., Hill, J.   +25 more
core   +1 more source

Alterations in salivary IgA levels in infectious and inflammatory disorders of upper respiratory tract

Research in Molecular Medicine, 2013
Background: The airway surfaces are one of the most common ways of entry of infectious agents. Oral cavity associated lymphoid tissues are inductive site of humoral immune responses in inflammatory and infectious disorders of the upper respiratory tract.
Abbas Hashemi, Saeid Abediankenari, Abdollah Madani   +2 more
doaj  

Infectious disease burden and antibiotic prescribing in primary care in Israel

Annals of Clinical Microbiology and Antimicrobials, 2018
Background Antibiotics are frequently prescribed at many of the visits to primary care clinics, often for conditions for which they provide no benefit, including viral respiratory tract infections.
Marcelo Low, Ronit Almog, Ran D. Balicer, Nicky Liberman, Raul Raz, Avi Peretz, Orna Nitzan   +6 more
doaj   +1 more source

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source