Longitudinal profiling of upper respiratory tract microbiota and metabolome in hospitalized COVID-19 convalescents: a 3-year prospective cohort study. [PDF]
Zhang Z +5 more
europepmc +1 more source
Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz +2 more
wiley +1 more source
NUT carcinoma of the upper respiratory tract: Two case reports and literature review. [PDF]
Jiang Y +6 more
europepmc +1 more source
ABSTRACT Sweet's syndrome is a rare neutrophilic dermatosis characterized by an acute onset of erythematous and infiltrative lesions. Diagnosis is based on clinical, histopathological, and laboratory findings. We propose that non‐invasive skin imaging techniques, such as line‐field confocal optical coherence tomography (LC‐OCT), may be beneficial for ...
Aleksandra Anderson +5 more
wiley +1 more source
Experimental inoculation of pigs with porcine parainfluenza virus 1 revealed pathological manifestations in the upper respiratory tract. [PDF]
Agerlin MV +9 more
europepmc +1 more source
Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis
ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense +4 more
wiley +1 more source
Prolonged dysregulation and pathological changes in the upper respiratory tract of SARS-CoV-2 infected hamsters. [PDF]
Liu F +14 more
europepmc +1 more source
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu +2 more
wiley +1 more source
MEK Inhibitor Associated Airway Injury in an Infant With Noonan Syndrome: A Case Report
An infant with Noonan syndrome treated with trametinib developed extensive mucosal sloughing of the upper and lower airway, followed by severe supraglottic scarring. Clinicians should consider airway toxicity as a potential adverse effect of MEK inhibitor therapy.
Veronica Drozdowski‐Nuccio +4 more
wiley +1 more source

