Allergy, EarlyView.Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian +18 more
wiley +1 more source
Combined cold-water immersion and breathwork may be associated with improved mental health and reduction in the duration of upper respiratory tract infection - a case-control study. [PDF]
Int J Circumpolar HealthCzarnecki J +2 more
europepmc +1 more source
Pathogenic Airway Bacteria and Local Immune Responses During Early‐Life Asthma‐Like Episodes
Allergy, EarlyView.This study investigates how Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis associate with airway immune responses during early‐life asthma‐like episodes, and compare these responses between children with and without asthma.
Mathilde Bundgaard Svendsen +12 more
wiley +1 more source
Increase in complicated upper respiratory tract infection in children during the 2022/2023 winter season-a post coronavirus disease 2019 effect? [PDF]
Pediatr RadiolMetz C, Schmid A, Veldhoen S.
europepmc +1 more source
Allergy, EarlyView.ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe +24 more
wiley +1 more source
Pericardial Tuberculosis in a Non-endemic Region Presenting as a Persistent Upper Respiratory Tract Infection With Negative Serology, Bronchial Washings, and Pleural Aspirate. [PDF]
CureusNolan P, Samad S, Kiernan T.
europepmc +1 more source
Allergy, EarlyView.In this Phase 2a trial, severely peanut‐allergic participants were randomized to abatacept versus placebo with peanut oral immunotherapy (OIT) for 24 weeks, followed by 12 weeks of OIT alone. No significant difference was observed for the primary efficacy outcome (the relative change from baseline in peanut‐specific/total IgE ratio at 24 weeks), but ...
Marie‐Lee Simard +12 more
wiley +1 more source
The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis
Allergy, EarlyView.ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith +9 more
wiley +1 more source
Project for Universal Management of Airways: guidelines for tracheal extubation
Anaesthesia, EarlyView.Summary Introduction Risk evaluation, strategy formulation and preparation are important to decreasing the incidence of adverse events associated with tracheal extubation. The focus of this guideline is tracheal extubation, but many of the principles outlined are relevant to all forms of discontinuation of airway management (tracheal extubation ...
Louise Ellard +14 more
wiley +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim This study examined how parents perceive and experience point‐of‐care testing in a paediatric emergency department and how these tests relate to the overall diagnostic process. Parents sought care for their children due to suspected respiratory tract infections. Methods Twenty parents participated in semi‐structured interviews.
Helle Mølsted Alvesson +3 more
wiley +1 more source