Results 251 to 260 of about 1,447,316 (308)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Longitudinal Syringomyelia, Cervical Dystonia, and Action Tremor in Trichorhinophalangeal Syndrome Type I - A Case Report. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Petko B, Weinberg BD, Vengoechea J, Gary M, Beach PA.   +4 more
europepmc   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Jackstone calculus within a renal cyst. [PDF]

Radiol Case Rep
Dennis D, Dhami S, Gattu R.
europepmc   +1 more source

Life-threatening upper gastrointestinal bleeding caused by pancreatic pseudocysts: A case report. [PDF]

Medicine (Baltimore)
Teng S, Huang M.
europepmc   +1 more source

A National Evaluation of Upper Extremity Weightlifting Injury Surveillance: The High Risk in Youth and Adults With an Underutilization in Older Adults. [PDF]

Orthop J Sports Med
Lee PM, Underhill J, Nishida C, Agonias K, Levine SB, Obana KK, Luzzi A, Chan S, Lee LSK, Weiss JM.   +9 more
europepmc   +1 more source

Students' Socio-Emotional Skills and Academic Outcomes After the PROMEHS Program: A Longitudinal Study in Two European Countries. [PDF]

Behav Sci (Basel)
Martinsone B, Simões C, Camilleri L, Conte E, Lebre P.   +4 more
europepmc   +1 more source