Results 31 to 40 of about 45,884 (175)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi, Margaux O. A. Forner, Pingyu Wang, Salim El Hadwe, Amy T. Jin, Gerwin Dijk, Kenneth Brinson, Juhwan Lim, Antonio Dominguez‐Alfaro, Carina Yi Jing Lim, Alberto Salleo, Damiano G. Barone, Guosong Hong, Mark L. Brongersma, Nicholas A. Melosh, George G. Malliaras, Scott T. Keene   +16 more
wiley   +1 more source

Intraoperative accuracy of O-arm navigated pedicle screw placement in the thoracic and lumbo-sacral regions of the spine – does localization matter? [PDF]

Folia Medica
Aim: The aim of the current study was to determine the intraoperative accuracy of pedicle screw placement using a 3D CT-assisted navigation system with an O-arm in the thoracic, lumbar, and sacral regions of the spine, as well as to investigate the ...
Ivo Kehayov, Atanas Davarski, Polina Angelova, Rumyana Stefanova, Borislav Kitov   +4 more
doaj   +3 more sources

Supraspinous ligament arc tangent guided freehand thoracic pedicle screw insertion technique: high parallelism between screws and upper endplate

Frontiers in Surgery, 2023
Research objectiveTo propose a technique for placing pedicle screws in the thoracic spine using the Supraspinous ligament Arc Tangent (SLAT) as a guide to increase the safety and stability of screw placement.Content and methodsA retrospective analysis of
Fushuai Peng, Meng Gao, Qiang Li, Zhensong Jiang, Fei Chen, Mingtong Sun, Yudong Lai, Haoyu Wang, Xingpeng Wang, Tao Li, Wen Zhang   +10 more
doaj   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Thoracic Spine Fracture in 18 Month Old Child; Case Report

Egyptian Spine Journal, 2017
Background Data: Spinal column trauma is relatively uncommon in pediatric patient and not frequently encountered among the 1st two years especially in the thoracic region.
Mohamed Elsebaey, Mohamed Okasha, Yasser Elkhwalka   +2 more
doaj   +1 more source

Association between diffuse idiopathic skeletal hyperostosis and thoracic kyphosis in patients with cervical myelopathy: a retrospective observational study

BMC Musculoskeletal Disorders, 2021
Background Diffuse idiopathic skeletal hyperostosis (DISH) is a structural abnormality of the thoracic spine that is known to impair posture. However, the relationship between DISH and sagittal balance in the whole spine is unclear.
Motoyoshi Takayuki, Hirai Takashi, Yoshii Toshitaka, Inose Hiroyuki, Matsukura Yu, Egawa Satoru, Kobayashi Yutaka, Utagawa Kurando, Hashimoto Jun, Kawabata Atsuyuki, Takahashi Takuya, Tanaka Tomoyuki, Okawa Atsushi   +12 more
doaj   +1 more source

Retrospective Analysis of Functional Pain among Professional Climbers

Applied Sciences, 2022
Climbing became one of the official Olympic sports in 2020. The nociplastic pain mechanism is indicated as important in professional sports. Functional pain, which has not been examined in climbers until now, can be an example of nociplastic pain.
Matuska Jakub, Jokiel Marta, Domaszewski Przemysław, Konieczny Mariusz, Pakosz Paweł, Dybek Tomasz, Wotzka Daria, Skorupska Elżbieta   +7 more
doaj   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

Posterior 360-Degree Stabilisation of the Upper Thoracic Spine: A Technical Note

Journal of Orthopaedic Surgery, 2007
Purpose. To describe a technique involving posterior 360-degree stabilisation of the upper thoracic spine: spinal cord decompression, posterior vertebral body replacement, and then posterior instrumentation and intercostal posterolateral vertebral ...
G Timbihurira, H Nakajima, S Kobayashi, R Sato, T Yayama, K Uchida, Y Horiuchi, H Baba   +7 more
doaj   +1 more source