Results 111 to 120 of about 606,045 (292)
Clinical Pharmacology &Therapeutics, EarlyView.Exposure–response (E–R) analyses of sunitinib in metastatic renal cell carcinoma (mRCC) have supported concentration‐guided dose escalation. However, such analyses may be biased when exposure metrics incorporate post‐baseline dose modifications, time‐varying apparent clearance, or baseline factors that influence both pharmacokinetics and clinical ...
Han Liu, Lena E. Friberg
wiley +1 more source
INTERNACIONALIZACIÓN EN LA INDUSTRIA DE LA MODA: EL CASO ZARA
Revista Galega de Economía, 2010 Basado en modelos como el de Uppsala y de la literatura de las formas de entrada en los mercados internacionales, este artículo tiene como objetivo demostrar el proceso de internacionalización de la cadena española Zara.
Belmiro do Nascimento João +3 more
doaj
Clinical Pharmacology &Therapeutics, EarlyView.Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong +10 more
wiley +1 more source
Overview of Regulatory Guidelines Related to Methods and Models for Small Populations
Clinical Pharmacology &Therapeutics, EarlyView.This paper provides an overview of approaches and related guidelines from the EMA, FDA, and ICH that are relevant for obtaining clinical evidence for small populations to support regulatory decision making. The approaches are grouped into three categories: (1) maximizing the attainable sample size, (2) adapting the trial design to deal with a small ...
Laurens Sluijterman +6 more
wiley +1 more source
, 2021 The question of a new art museum in Uppsala has been under constant debate in recent years. On 27 May 2020, the municipal board in Uppsala made a decision to locate an art museum at either Uppsala Castle or the Kaniken district.Uppsala is today facing a major change, where the conditions for stores change in step with e-commerce. It has so far happened
openaire +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Aberrant antigen expression on mast cells (MCs) is one of the most accurate diagnostic markers for clonal MC diseases (CMCD). Although the coexistence of normal and pathologic MCs is frequently seen, the disease characteristics associated with it have been minimally investigated.
Abdulrazzaq Alheraky +6 more
wiley +1 more source
, 1921 Jonas Hallenbergs anteckningar och samlingar, till Gustaf II Adolfs historia i Uppsala universitetsbibliotek, av A.B. Carlsson. -- Några ord om utländska kartor i Uppsala universitetsbibliotek, av N.E. Taube.
Uppsala universitetsbibliotek.
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