Results 81 to 90 of about 628,251 (363)
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
An open partition \pi{} [Cod09a, Cod09b] of a tree T is a partition of the vertices of T with the property that, for each block B of \pi, the upset of B is a union of blocks of \pi. This paper deals with the number, NP(n), of open partitions of the tree,
Codara, Pietro +3 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Performance analysis of a generalized upset detection procedure [PDF]
A general procedure for upset detection in complex systems, called the data block capture and analysis upset monitoring process is described and analyzed.
Blough, Douglas M., Masson, Gerald M.
core +1 more source
Ultrasonic angle beam standard reflector [PDF]
A method that provides an impression profile in a reference standard material utilized in inspecting critically stressed components with pulsed ultrasound is described. A die stamp having an I letter is used to impress the surface of a reference material.
Berry, R. F., Jr.
core +1 more source
Upset in Response to a Sibling’s Partner’s Infidelity
Existing evidence suggests that the psychological design of romantic jealousy differs for men and women: Men are more likely than women to report greater upset in response to a partner’s sexual than emotional infidelity, whereas women are more likely ...
Dafni Hellstrand, Elisavet Chrysochoou
doaj +1 more source
Controlled Study of Atomoxetine in ADHD
Researchers at the Department of Psychiatry, University of Nebraska Medical Center, Omaha, and other centers in the US conducted an 8-week, double-blind, placebo-controlled study of atomoxetine for treatment of ADHD in 101 children 5- and 6-years of age ...
J Gordon Millichap
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

