Results 81 to 90 of about 632,890 (360)

Controlled Study of Atomoxetine in ADHD

open access: yesPediatric Neurology Briefs, 2011
Researchers at the Department of Psychiatry, University of Nebraska Medical Center, Omaha, and other centers in the US conducted an 8-week, double-blind, placebo-controlled study of atomoxetine for treatment of ADHD in 101 children 5- and 6-years of age ...
J Gordon Millichap
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Gravitational Correction to Running of Gauge Couplings

open access: yes, 2005
We calculate the contribution of graviton exchange to the running of gauge couplings at lowest non-trivial order in perturbation theory. Including this contribution in a theory that features coupling constant unification does not upset this unification ...
E. Kiritsis   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Utilization of the wing-body aerodynamic analysis program [PDF]

open access: yes
The analysis program was used to investigate several aircraft characteristics. The studies performed included vehicle stability analysis, determination of upwash angle, identification of nonpotential flow, launch dynamics, and wake vortex upset loads ...
Curry, R. E.
core   +1 more source

Deformation Characteristic and Microstructure Evolution of Gh4169 Alloy Induced by Axial Upsetting and Axial Rotary Forging

open access: green, 2022
Jianguo Wang   +6 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Low-Power and High-Performance Double-Node-Upset-Tolerant Latch Using Input-Splitting C-Element

open access: yesSensors
Data accuracy is critical for sensor systems. As essential components of digital circuits within sensor systems, nanoscale CMOS latches are particularly susceptible to single-node upsets (SNUs) and double-node upsets (DNUs), which can lead to data errors.
Qi Chen   +4 more
doaj   +1 more source

Upset in Response to a Sibling’s Partner’s Infidelity

open access: yesEvolutionary Psychology, 2015
Existing evidence suggests that the psychological design of romantic jealousy differs for men and women: Men are more likely than women to report greater upset in response to a partner’s sexual than emotional infidelity, whereas women are more likely ...
Dafni Hellstrand, Elisavet Chrysochoou
doaj   +1 more source

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