Results 81 to 90 of about 225 (196)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Safety culture influence on safety performance of a post-combustion carbon capture facility

Heliyon
This article explores the influence of safety culture (as a subset of organizational culture) on the safety performance of a post-combustion carbon capture facility.
Maryam Shourideh, Sirous Yasseri, Hamid Bahai   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Process parameter optimization and bonding mechanism in dissimilar S45C/A6061 joints via novel sacrificing-sheet linear friction welding

Journal of Advanced Joining Processes
Sacrificing-sheet linear friction welding (SSLFW) is a novel solid-state joining technique developed to address the challenges of dissimilar welding between S45C steel and A6061 aluminum alloy, which are difficult to join using conventional linear ...
Furkan Khan, Takuya Miura, Yoshiaki Morisada, Kohsaku Ushioda, Hidetoshi Fujii   +4 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A Measurement of Contact-Pressure Distributions in the Upsetting of Cylindrical Billets

JSME international journal. Ser. 1, Solid mechanics, strength of materials, 1989
KOJIMA, Yukio, MIZUNO, Takaji
openaire   +2 more sources

Identification of key cardiovascular disease predictive factors from the China Health and Retirement Longitudinal Study dataset using machine learning-based algorithms

Journal of Translational Medicine
Background Cardiovascular diseases (CVDs) are a leading cause of death but are largely preventable. Consequently, devising effective predictive models to identify high-risk factors, and subsequently shape earlier interventional strategies, are of great ...
Jiayuan Chen, Cheng Fan, Yu Wang, Yuou Lei, Haochuan Jiang, Tianyao Gong, Chuting Tang, Dongxi Hong, Chuanfang Cheng, Pei Mo, Chengfeng Luo, Wenchao Ou, Shiming Liu, Yun Zhong, Chongyu Zhang   +14 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source