Results 51 to 60 of about 1,698,123 (315)

A systematic review of approaches to achieving equitable childhood immunization (0–5 years) among First Nations populations in high income OECD countries

Journal of Health Equity
Despite long-standing immunization programs, inequities in vaccination coverage persist for First Nations children in high-income countries. Previous reviews identified coverage gaps but rarely assessed intervention quality through a First Nations ...
Jennifer White, Brittany Wilson, Katrina Clark, Catherine King, Katarzyna T. Bolsewicz, Jessica Kaufman, Yasmin Mohamed, Margie Danchin, David N. Durrheim   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Derivation of a dynamic model of the kinetics of nitrogen uptake throughout the growth of lettuce : calibration and validation [PDF]

A kinetic model of nitrogen (N) uptake throughout growth was developed for lettuce cultivated in nutrient solution under varying natural light conditions.
Zhang, Kefeng, Burns, Ian G.
core   +1 more source

Picoeukaryote distribution in relation to nitrate uptake in the oceanic nitracline [PDF]

, 2014
We investigated the relationship between picoeukaryote phytoplankton (
Painter, Stuart C., Tarran, Glen A., Patey, M.D., Torres-valdes, S., Tarran, GA, Torres-Valdes, Sinhue, Tarran, G.A., Painter, SC, Torres-Valdés, S, Patey, MD, Patey, Matthew D., Painter, S.C.   +11 more
core   +1 more source

Effects of a demand-led evidence briefing service on the uptake and use of research evidence by commissioners of health services: a controlled before-and-after study

Health Services and Delivery Research, 2017
Background: The Health and Social Care Act 2012 (Great Britain. Health and Social Care Act 2012. London: The Stationery Office; 2012) has mandated research use as a core consideration of health service commissioning arrangements.
Paul M Wilson, Kate Farley, Liz Bickerdike, Alison Booth, Duncan Chambers, Mark Lambert, Carl Thompson, Rhiannon Turner, Ian S Watt   +8 more
doaj   +1 more source

Assessment of Influenza Vaccine Uptake According to the Presence of a Chronic Disease

Vaccines, 2023
Patients diagnosed with a chronic disease are at higher risk of influenza complications. This investigation aimed to estimate influenza vaccine uptake rates among healthy subjects and patients with chronic diseases, and to identify barriers to and ...
Ibrahim M. Gosadi, Basem Zogel, Samar Alfaifi, Faisal Abusageah, Khalid M. Hakami, Taif Zogel, Tahani Altubayqi, Afnan Darsi, Ghaida Almuhaysin, Ali Ghalibi, Mohammed Alhazmi, Khulud Mahla   +11 more
doaj   +1 more source

On Guanidinium and Cellular Uptake [PDF]

The Journal of Organic Chemistry, 2014
Guanidinium-rich scaffolds facilitate cellular translocation and delivery of bioactive cargos through biological barriers. Although impressive uptake has been demonstrated for nonoligomeric and nonpept(o)idic guanidinylated scaffolds in cell cultures and animal models, the fundamental understanding of these processes is lacking.
Wexselblatt, Ezequiel, Esko, Jeffrey D, Tor, Yitzhak   +2 more
openaire   +5 more sources