Results 121 to 130 of about 18,041 (209)

A Review of Solid-State LiDAR Principles and Metasurface-Based LiDAR Sensors. [PDF]

Sensors (Basel)
Demirbas E, Boucher B, Baker M, Andrews J, Cruz W, Mueller S, Serna-Otalvaro S.   +6 more
europepmc   +1 more source

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

Contrasting melt regime in the Ice Grounding Zone of Thwaites Glacier, West Antarctica. [PDF]

Proc Natl Acad Sci U S A
Gadi R, Rignot E, Menemenlis D, Scheuchl B.   +3 more
europepmc   +1 more source

Two-Dimensional Layered Organic-Inorganic Hybrid Perovskite Thin-Film Fabrication by Langmuir-Blodgett and Intercalation Techniques. [PDF]

ACS Omega, 2022
Miura YF, Akagi Y, Hishida D, Takeoka Y.
europepmc   +1 more source

A Versatile Three Dimensional Traction Force Microscopy Framework for Uncovering the Mechanics of Bio‐Adhesion

Advanced Science, EarlyView.
This study introduces a versatile platform for quantifying three dimensional traction forces at bio‐adhesive interfaces. Integrating in situ stereo‐digital image correlation with finite element simulations allows for precise measurement of microscale displacements and traction forces in both dry and wet conditions.
Yingwei Hou, Fusheng Wang, Tao Liu
wiley   +1 more source

Multi-layer self-calibrated algorithm for transabdominal fetal pulse oximetry: simulation and <i>in vivo</i> validation. [PDF]

JPhys Photonics
Wu J, Debreczeny MP, Hanumara NC, Ray N, Jayet B, Andersson-Engels S, Kainerstorfer JM.   +6 more
europepmc   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

Large-Scale Flat Silk Cocoons as a Highly Effective Salt-Resistant Low-Cost Solar-Powered Evaporator. [PDF]

Adv Sci (Weinh)
Wei T, Cheng Q, Lu L, Wan Q, Wu Q, Shao R, Xu Z, Wang J, Shuai Y, Mao C, Yang M.   +10 more
europepmc   +1 more source

Experimental Results on the Effect of Surface Structures on the Flame Propagation Velocity of PMMA in Microgravity [PDF]

, 2017
Jomaas, Grunde
core  

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source