Results 61 to 70 of about 32,450 (192)

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, Volume 600, Issue 1, Page 99-108, January 2026.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

KONSTRUKSI TRIPLE DISRUPTAN GEN PENGKODE PROTEIN FOSFATASE DAN PROTEIN KINASE Saccharomyces cerevisiae

Jurnal Kimia Riset, 2016
Abstrak Konstruksi triple disruptan pada Saccharomyces cerevisiae dibuat dengan menyilangkan (crossing) atau melakukan mating antara strain BY4739 (MATa ura3D0 leu2D0 lys2D0 kin3D::KanMX) dengan strain SH6793 (MATa ptp2D::CgHIS3 msg5D::CgLEU2 ura3-52 ...
Hermansyah Hermansyah, Susilawati Susilawati   +1 more
doaj   +1 more source

Contributions of histone H3 nucleosome core surface mutations to chromatin structures, silencing and DNA repair. [PDF]

PLoS ONE, 2011
Histone H3 mutations in residues that cluster in a discrete region on the nucleosome surface around lysine 79 of H3 affect H3-K79 methylation, impair transcriptional silencing in subtelomeric chromatin, and reveal distinct contributions of histone H3 to ...
Michel Fink, Jeffrey S Thompson, Fritz Thoma   +2 more
doaj   +1 more source

Investigating the mechanism of aluminum resistance conferred by aluminum resistance protein 1

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Aluminum does not play any role in essential biological processes, but in acidic conditions it becomes biologically reactive and highly toxic even at low concentrations. Eukaryotes have developed numerous strategies for detoxification, one of which relies on membrane proteins.
Pavlo Stehantsev, Artem Stetsenko, Pavla Herynková, Andrei Zupnik, Carsten Takens, Olga Zimmermannova, Hana Sychrova, Albert Guskov   +7 more
wiley   +1 more source

CRISPR/Cas9-Mediated Gene Replacement in the Fungal Keratitis Pathogen Fusarium solani var. petroliphilum

Microorganisms, 2019
Fungal keratitis (FK) is a site-threatening infection of the cornea associated with ocular trauma and contact lens wear. Members of the Fusarium solani species complex (FSSC) are predominant agents of FK worldwide, but genes that support their corneal ...
Jorge D. Lightfoot, Kevin K. Fuller
doaj   +1 more source

Mutation in IRO1 Tightly Linked with URA3 Gene Reduces Virulence of Candida albicans [PDF]

Microbiology and Immunology, 2005
AbstractGene deletion in the pathogenic fungus Candida albicans has relied heavily on a URA3 cassette and a recipient Aura3 strain CAI4. The IRO1 gene adjacent to URA3 was inadvertently deleted during construction of CAI4. We report here that a mutation in IRO1 reduces virulence of C. albicans.
Hiroji, Chibana, Jun, Uno, Tamaki, Cho, Yuzuru, Mikami   +3 more
openaire   +2 more sources

Development of an eco‐friendly RNAi yeast attractive targeted sugar bait that silences the shaker gene in spotted‐wing drosophila, Drosophila suzukii

Pest Management Science, Volume 82, Issue 1, Page 732-741, January 2026.
This study discusses a promising new attractive targeted sugar bait (ATSB) technology using yeast that expresses shRNA targeting essential genes in the fruit pest spotted‐wing drosophila (SWD). The yeast, which is delivered using soda as a sugar bait, could one day be an effective component in integrated SWD control programs.
Keshava Mysore, Jackson Graham, Teresia M. Njoroge, Akilah T. M. Stewart, Saisuhas Nelaturi, Molly Duman‐Scheel   +5 more
wiley   +1 more source

Competition between binding partners of yeast Pex3 affects peroxisome biology

The FEBS Journal, Volume 293, Issue 1, Page 175-195, January 2026.
Pex3 is a peroxisomal membrane protein (PMP) that specifically recruits several binding partners. In the yeast Hansenula polymorpha, Atg30 (pexophagy), Inp1 (inheritance) and Pex19 (receptor for new PMPs) associate with Pex3. Overexpression of any of these proteins affects peroxisomal processes because these proteins compete for binding to Pex3.
Eline M. F. de Lange, Grzegorz Chojnowski, Jérôme Bürgi, Rifka Vlijm, Matthias Wilmanns, Ida J van der Klei   +5 more
wiley   +1 more source

Exponential Clonal Expansion of 5-Fluorocytosine–Resistant Candida tropicalis and New Insights into Underlying Molecular Mechanisms

Emerging Infectious Diseases
In 2022, we initiated systematic 5-fluorocytosine susceptibility testing of Candida spp. isolates in Denmark; we observed a bimodal MIC distribution in C. tropicalis, with MICs >16 mg/L in half the isolates.
Nissrine Abou-Chakra, Karen Marie Thyssen Astvad, Jan Martinussen, Amalie Sofie Eilsø Munksgaard, Maiken Cavling Arendrup   +4 more
doaj   +1 more source

Efficient CRISPR-Cas9 Gene Disruption System in Edible-Medicinal Mushroom Cordyceps militaris

Frontiers in Microbiology, 2018
Cordyceps militaris is a well-known edible medicinal mushroom in East Asia that contains abundant and diverse bioactive compounds. Since traditional genome editing systems in C.
Bai-Xiong Chen, Bai-Xiong Chen, Tao Wei, Tao Wei, Zhi-Wei Ye, Zhi-Wei Ye, Fan Yun, Lin-Zhi Kang, Hong-Biao Tang, Hong-Biao Tang, Li-Qiong Guo, Li-Qiong Guo, Jun-Fang Lin, Jun-Fang Lin   +13 more
doaj   +1 more source