Results 241 to 250 of about 1,016,429 (298)

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Optimizing mung bean productivity and root morphology with biofertilizers for sustainable farming. [PDF]

Sci Rep
Yousefi A, Nabati J, Mirzaeetalarposhti R, Malakshahi Kurdestani A.   +3 more
europepmc   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Urea and potassium nitrate synergy in sesame cultivation: boosting growth, yield, and antioxidant resilience through tailored nitrogen fertilization. [PDF]

Sci Rep
Saad-Allah KM, Elkelish A, Abu-Elsaoud AM, Al-Robai SA, Essa D, Badji A, Alammari B, Abo-Shanab WA.   +7 more
europepmc   +1 more source

Solar-driven direct coupling of atmospheric CO₂ with ammonia for urea synthesis. [PDF]

Nat Commun
Zhang Z, Huang Q, Xie Y, Zhang B, Zhao Q, Huang X, Yang N, Ji H, Chen C, Sheng H, Zhao J.   +10 more
europepmc   +1 more source

Urea Transporters in Cancer: Emerging Roles and Their Clinical Implications. [PDF]

Biomedicines
Sun H, Yang Q, Ding M, Li S, Xue Y.
europepmc   +1 more source

Techno-Economic Assessment of Industrial Symbiosis Between Steel and Urea Plants: The INITIATE Process. [PDF]

Energy Fuels
Zecca N, Lücking L, van Dijk HAJ, Manzolini G.   +3 more
europepmc   +1 more source

Improved photocatalytic activity and enhanced germination rate of <i>Oryza sativa</i> and urea sensor development utilizing fabricated NiO·SrCO₃·ZnO nanomaterials. [PDF]

RSC Adv
Dey S, Saha PC, Subhan MA, Alam MM, Al-Mamun M, Hossain D, Azad AK, Alahmari SD, Albishri A, Alzahrani KA, Rahman MM.   +10 more
europepmc   +1 more source

Mass spectrometry detects folding intermediates populated during urea-induced protein denaturation. [PDF]

Chem Sci
Österlund N, Jordan JS, Renzi E, Szekeres GP, Pagel K.   +4 more
europepmc   +1 more source