Results 311 to 320 of about 1,298,773 (390)

BIOSYNTHESIS OF UREA

, 1949
S. Ratner, Anne. Pappas
openalex   +1 more source

Silk‐Fibroin as Biocompatible and Bioresorbable Enzyme Immobilization Matrix for Screen‐Printed Amperometric Glucose Biosensors

Advanced Sensor Research, EarlyView.
Silk‐fibroin is applied as an immobilization matrix for a biocompatible and bioresorbable amperometric glucose biosensor. The immobilization matrix is optimized with regard to silk‐fibroin content, enzyme loading, and water solubility. The optimized silk‐fibroin matrix is compared to a BSA/glutaraldehyde‐based matrix.
Kevin A. Janus, Stefan Achtsnicht, Benedetta Isella, Alexander Kopp, Koichiro Miyamoto, Tatsuo Yoshinobu, Michael Keusgen, Michael J. Schöning   +7 more
wiley   +1 more source

Astrocytic Ornithine Decarboxylase 1 in Alzheimer's Disease. [PDF]

Exp Neurobiol
Bhalla M, Lee CJ.
europepmc   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Advanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu   +14 more
wiley   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Influence of Different Precursors on Properties and Photocatalytic Activity of g-C₃N₄ Synthesized via Thermal Polymerization. [PDF]

Materials (Basel)
Briševac D, Gabelica I, Radovanović-Perić F, Tolić Čop K, Matijašić G, Ljubas D, Ćurković L.   +6 more
europepmc   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

Synthesis and Fluorescence Mechanism of Nitrogen-Doped Carbon Dots Utilizing Biopolymer and Urea. [PDF]

Molecules
Yorozuya H, Ashrafi NE, Sato K, Islam A, Fukae R, Tagashira Y, Iimori T.   +6 more
europepmc   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

The urea-to-creatinine ratio as an emerging biomarker in critical care: a scoping review and meta-analysis. [PDF]

Crit Care
Paulus MC, Melchers M, van Es A, Kouw IWK, van Zanten ARH.   +4 more
europepmc   +1 more source