A study of allosteric binding behaviour of a 1,3-alternate thiacalix[4]arene-based receptor using fluorescence signal [PDF]
, 2014 A novel heteroditopic thiacalix[4]arene receptor L possessing 1,3-alternate conformation, which contains two pyrene moieties attached to the lower rim via urea linkages together with a crown ether moiety appended at the opposite side of the thiacalix[4 ...
Jin, Cheng Cheng +7 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Bayesian approach for evaluating ammonia volatilization nitrogen losses in fertilizers applied to coffee plants [PDF]
Ciência e AgrotecnologiaAmmonia loss through volatilization is an important reason for the lower effectiveness of nitrogen fertilizers in coffee plants. The Bayesian approach uses informative prior distributions, which help improve the precision and accuracy of inferences ...
Mírian Rosa +2 more
doaj +1 more source
Soil Systems, 2023 Controlled-release urea fertilization is an innovative approach and effective means to reduce the loss of nitrogen and enhance fertilizer use efficiency to optimize crop yield while minimizing the environmental impact.
Samar Swify +2 more
doaj +1 more source
The effect of dietary nitrogen on nitrogen partitioning and milk production in grazing dairy cows : A thesis presented in partial fulfilment of the requirements for the Master of Animal Science at Massey University Palmerston North, New Zealand [PDF]
, 2016 Two experiments were conducted during spring (8th October to 12th November 2009) as part of a larger study, to study the effects of increasing levels of crude protein (CP) in pasture on milk production, dry matter intake (DMI) and nitrogen (N ...
Hendriks, Stacey
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Student's Journal of Health Research Africa, 2023 Background: Kidney failure and nephropathy, defined as a dysfunctional kidney with a decline in ultrafiltration and a rise in blood urea and creatinine levels, are frequently caused by diabetes.
Prashant Kumar +2 more
doaj +1 more source
Hydration of urea and alkylated urea derivatives
The Journal of Chemical Physics, 2018 Compressibility data and broadband dielectric spectra of aqueous solutions of urea and some of its alkylated derivatives have been evaluated to yield their numbers Nh of hydration water molecules per molecule of solute. Nh values in a broad range of solute concentrations are discussed and are compared to hydration numbers of other relevant molecules ...
openaire +3 more sources
pH-dependent gating mechanism of the Helicobacter pylori urea channel revealed by cryo-EM. [PDF]
, 2019 The urea channel of Helicobacter pylori (HpUreI) is an ideal drug target for preventing gastric cancer but incomplete understanding of its gating mechanism has hampered development of inhibitors for the eradication of H. pylori. Here, we present the cryo-
Cui, Yanxiang +6 more
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source