Results 51 to 60 of about 11,659 (222)

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

iMetaOmics, Volume 3, Issue 1, March 2026.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu, Zhibiao Li, Lin Yang, Jun Zheng, Weijia Li, Rulin Liao, Wenxue Huang, Boyuan Sun, Zhuohang Li, Cunzhen Ma, Xunguo Yang, Zongwei Wang, Jie Zhao, Bisheng Cheng, Peng Wu   +14 more
wiley   +1 more source

Novel insights into neuroinflammation: bacterial lipopolysaccharide, tumor necrosis factor α, and Ureaplasma species differentially modulate atypical chemokine receptor 3 responses in human brain microvascular endothelial cells

Journal of Neuroinflammation, 2018
Background Atypical chemokine receptor 3 (ACKR3, synonym CXCR7) is increasingly considered relevant in neuroinflammatory conditions, in which its upregulation contributes to compromised endothelial barrier function and may ultimately allow inflammatory ...
Christine Silwedel, Christian P. Speer, Axel Haarmann, Markus Fehrholz, Heike Claus, Mathias Buttmann, Kirsten Glaser   +6 more
doaj   +1 more source

Role of Ureaplasma urealyticum and Ureaplasma parvum as Risk Factors for Cervical Dysplasia with Human Papillomavirus

Journal of Pure and Applied Microbiology, 2023
Human papillomavirus (HPV) can be transmitted sexually and causes cervical malignancies in women. Among the risk factors, sexually transmitted infections (STIs) caused by bacteria have raised concerns because they are asymptomatic and persistent and can ...
Mardhia Mardhia, Andi Yasmon, Junita Indarti, Lisnawati Rachmadi   +3 more
doaj   +1 more source

How the Cervical Microbiota Contributes to Cervical Cancer Risk in Sub-Saharan Africa [PDF]

, 2020
Despite ongoing efforts, sub-Saharan Africa faces a higher cervical cancer burden than anywhere else in the world. Besides HPV infection, definitive factors of cervical cancer are still unclear.
Angeletti, Peter C., Kahesa, Crispin, Klein, Cameron, Mwalselage, Julius, West, John T., Wood, Charles   +5 more
core   +1 more source

The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development [PDF]

, 2017
Chorioamnionitis is associated with adverse neurodevelopmental outcomes in preterm infants. Ureaplasma spp. are the microorganisms most frequently isolated from the amniotic fluid of women diagnosed with chorioamnionitis.
Barre, F.P.Y., Beeton, Michael L., Cillero-Pastor, B., Gussenhoven, R., Heeren, R.M.A., Jobe, A.H., Kallapur, S.G., Kemp, M.W., Kessels, L., Kramer, B.W., Ophelders, D.R.M.G., Payne, M.S., Rutten, B.P., Spiller, O.B., Stevens, B., Stocks, S.J., Wolfs, T.G.A.M.   +16 more
core   +4 more sources

Mechanisms and Therapeutic Implications of Microbiome‐Mediated Immune Dysregulation in Recurrent Pregnancy Loss and Implantation Failure

American Journal of Reproductive Immunology, Volume 95, Issue 3, March 2026.
ABSTRACT Problem Recurrent pregnancy loss (RPL), defined as two or more consecutive pregnancy losses before 20 weeks of gestation, affects 1%–5% of couples of reproductive age worldwide. Growing evidence indicates a role for the microbiome in reproductive health, particularly in unexplained RPL.
Wael Bahia, Ismail Soltani, Salima Ferchichi, Wassim Y. Almawi   +3 more
wiley   +1 more source

Impact of human papillomavirus and coinfection with other sexually transmitted pathogens on male infertility

Asian Journal of Andrology
This study primarily aimed to investigate the prevalence of human papillomavirus (HPV) and other common pathogens of sexually transmitted infections (STIs) in spermatozoa of infertile men and their effects on semen parameters.
Xin Fan, Ya Xu, Li-Feng Xiang, Lu-Ping Liu, Jin-Xiu Wan, Qiu-Ting Duan, Zi-Qin Dian, Yi Sun, Ze Wu, Yun-Hua Dong   +9 more
doaj   +1 more source

More than just inflammation: Ureaplasma species induce apoptosis in human brain microvascular endothelial cells

Journal of Neuroinflammation, 2019
Background Ureaplasma species (spp.) are commonly regarded as low-virulent commensals but may cause invasive diseases in immunocompromised adults and in neonates, including neonatal meningitis. The interactions of Ureaplasma spp.
Christine Silwedel, Axel Haarmann, Markus Fehrholz, Heike Claus, Christian P. Speer, Kirsten Glaser   +5 more
doaj   +1 more source

Low-pathogenicity Mycoplasma spp. alter human monocyte and macrophage function and are highly prevalent among patients with ventilator-acquired pneumonia. [PDF]

, 2016
BACKGROUND: Ventilator-acquired pneumonia (VAP) remains a significant problem within intensive care units (ICUs). There is a growing recognition of the impact of critical-illness-induced immunoparesis on the pathogenesis of VAP, but the mechanisms remain
Conway Morris, A, Gadsby, NJ, Hellyer, TP, McKenna, JP, McMullan, R, Nolan, TJ, Rennie, J, Robb, CT, Rossi, AG, Simpson, AJ, Templeton, KE, Walsh, TS   +11 more
core   +2 more sources

Co-infection of human papillomavirus and other sexually transmitted bacteria in cervical cancer patients in the Philippines

Gynecologic Oncology Reports, 2022
Cervical cancer is the fourth most common cancer in women globally. Based on several epidemiologic studies, human papillomavirus is strongly associated with cervical neoplasia.
Ourlad Alzeus G. Tantengco, Yukiko Nakura, Michinobu Yoshimura, Fumiko Nishiumi, Erlidia F. Llamas-Clark, Itaru Yanagihara   +5 more
doaj   +1 more source