Results 41 to 50 of about 30,710 (255)

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Urine Proteome Biomarkers in Kidney Diseases. I. Limits, Perspectives, and First Focus on Normal Urine

Biomarker Insights, 2016
Urine proteome is a potential source of information in renal diseases, and it is considered a natural area of investigation for biomarkers. Technology developments have markedly increased the power analysis on urinary proteins, and it is time to confront
Laura Santucci, Maurizio Bruschi, Giovanni Candiano, Francesca Lugani, Andrea Petretto, Alice Bonanni, Gian Marco Ghiggeri   +6 more
doaj   +1 more source

Comparative Study of Psychological Distress Profile and Maladaptive Personality Dimensions (PID-5) Among Victim and Persecutor Individuals Referring to Domestic Violence Problem in Social Emergency (123) [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: domestic violence is a type of social harm that can have adverse effects on different aspects of human life, of which the most important ones can be psychological outcomes such as depression and anxiety that can cost a lot to both
Karim Babaei, , Marziyeh Sattari, Saeedeh Noor Mohammadi Ahari   +3 more
doaj  

Food Hygiene Practices of Vendors and Microbiological Quality of Ready to Eat Foods at Night Markets

AgriFood: Journal of Agricultural Products for Food, EarlyView.
This study investigates the relationship between food hygiene practices among night market vendors and the microbiological quality of ready to eat (RTE) foods sold at night markets. ABSTRACT Ready to eat (RTE) foods are popular options in night markets due to their convenience, affordability, and accessibility.
Yu Xin Soon, Kai Wen Koay, Seok Tyug Tan, Seok Shin Tan, Hariyono Hariyono, Chin Xuan Tan   +5 more
wiley   +1 more source

Monocytes in Uremia

Toxins, 2020
Monocytes play an important role in both innate immunity and antigen presentation for specific cellular immune defense. In patients with chronic renal failure, as well as those treated with maintenance hemodialysis, these cells are largely dysregulated ...
Matthias Girndt, Bogusz Trojanowicz, Christof Ulrich   +2 more
doaj   +1 more source

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

Animal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani, Mahnaz Torfeh, Fatemeh Ashrafian, Niloofar Rezaie, Mohsen Mohammadi, Shadi Aghamohammad, Mahdi Rohani   +6 more
wiley   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

The Role of Health-Promoting Behaviors in Predicting the Quality of Life of Pregnant Women

Journal of Research Development in Nursing and Midwifery, 2017
 Introduction: High quality of life during the pregnancy is of great importance for both mother and the fetus. In order to identify factors affecting the quality of life of pregnant women, this study was conducted to show the role of health ...
Sajad Basharpoor, Hadis Heidarirad, Esmael Soleimani, Behroz Degdar   +3 more
doaj   +2 more sources

From hundreds to thousands: Widening the normal human Urinome

Data in Brief, 2014
The limits on protein detection in urine are unknown. Improving the analytical approach to detection would increase the number of identified proteins and potentially strengthen their predictive potential in diseases.
Laura Santucci, Giovanni Candiano, Andrea Petretto, Maurizio Bruschi, Chiara Lavarello, Elvira Inglese, Pier Giorgio Righetti, Gian Marco Ghiggeri   +7 more
doaj   +1 more source

Calpain is activated in experimental uremia: Is calpain a mediator of uremia-induced myocardial injury? [PDF]

, 2003
Calpain is activated in experimental uremia: Is calpain a mediator of uremia-induced myocardial injury?BackgroundThe cysteine proteases calpain and caspase-3 are known mediators of cell death. The aim of this study was to assess their contribution to the
Alistair M.S. Chesser, Harwood, Steven M., Allen, David A., Yaqoob, Muhammad M., Martin J. Raftery, David I. New, New, David I., David A. Allen, Chesser, Alistair M.S., Steven M. Harwood, Raftery, Martin J., Muhammad M. Yaqoob   +11 more
core   +1 more source