Results 101 to 110 of about 21,464 (246)

Gene therapy in renal diseases

, 2004
Gene therapy in renal diseases. Kidney-targeted gene therapy could be an ideal treatment for renal diseases since the therapeutic molecule is limited in the kidney and the systemic effect may be minimized.
Isaka, Yoshitaka, Mizui, Masayuki, Imai, Enyu, Takabatake, Yoshitsugu   +3 more
core   +1 more source

Iatrogenic ureteric injuries after abdominal surgery: a systematic review and meta‐regression from the European Association of Urology Endourology Section

BJU International, Volume 138, Issue 1, Page 45-56, July 2026.
Objective To systematically evaluate management strategies and associated outcomes of iatrogenic ureteric injuries, focusing on clinical success, renal unit loss, and the need for subsequent endoscopic or reconstructive procedures. Patients and Methods A pre‐registered protocol (CRD420251184018) guided a comprehensive search of PubMed and EMBASE ...
Pietro Scilipoti, Nicola Nannola, Federico Zorzi, Carlos Gonzalez Gonzalez, Marie Chicaud, Luigi Candela, Stefano Moretto, Carlotta Nedbal, Tzevat Tefik, Luca Villa, Eugenio Ventimiglia, Andrea Salonia, Alberto Briganti, Francesco Montorsi, Bhaskar K. Somani, Steeve Doizi, Olivier Traxer, Frederic Panthier   +17 more
wiley   +1 more source

Homozygous Loss‐of‐Function Variant in SLC20A1 Coding for Ubiquitous Phosphate Transporter PiT1 Is Associated With Multiple Developmental Abnormalities

Clinical Genetics, Volume 110, Issue 1, Page 64-72, July 2026.
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis, Céline Huber, Wendy Chung, Christine Leroy, Pauline Parisot, Regis Gaudin, Mohamad Zaidan, Valérie Cormier‐Daire, Gérard Friedlander, Yoel Hirsch   +9 more
wiley   +1 more source

Reframing Wnt/β‐Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley   +1 more source

HMGB1-mediated macrophage polarization to M2 phenotype promotes ureteral stricture: therapeutic potential of HMGB1 inhibitors

European Journal of Medical Research
Background Ureteral stricture is a common condition characterized by fibrotic narrowing of the ureter, often resulting in obstruction and impaired renal function.
Jie Zheng, Lingsong Tao, Yingqing Liu, Yang Zhang, Li Cheng, Zongyao Hao   +5 more
doaj   +1 more source

Executive summary of American Radium Society Appropriate Use Criteria for the treatment of locoregionally recurrent rectal cancer

Cancer, Volume 132, Issue 12, 15 June 2026.
Abstract This literature‐based systematic review and associated guidelines provide evidence‐based paradigms for the management of locoregionally recurrent rectal cancer (LRRC). This multispecialty committee included gastrointestinal radiation and medical oncology, gastroenterology, radiology, and colorectal surgery.
Eric D. Miller, Krishan R. Jethwa, Eric Dozois, Zhaohui Jin, Gerard Abood, Dmitriy Akselrod, Joseph Attallah, D. Chamil Codipilly, Christopher J. Anker, Christopher L. Hallemeier, Leslie C. Hassett, Timothy Kennedy, Percy Lee, Diane C. Ling, Neil B. Newman, Navesh Sharma, William Small Jr., Leila Tchelebi, Suzanne Russo   +18 more
wiley   +1 more source

10-Year Experience with Reinforced Ureteral Stents for Malignant Ureteral Obstruction

Research and Reports in Urology, 2021
Benoît Vogt,1 Laure-Hélène Blanchet2 1Department of Urology, Polyclinique de Blois, La Chaussée Saint-Victor, 41260, France; 2Department of Public Health, Hôpital Saint-Antoine (AP-HP), Paris, 75012, FranceCorrespondence: Benoît VogtDepartment of Urology,
Vogt B, Blanchet LH
doaj  

Minimmally invasive resolution of a left ureteral stenosis after Schistosoma haematobium infection

, 2019
Genitourinary schistosomiasis is an acquired cause of urinary tract diseases, especially hematuria. Schistosoma haematobium can infect travelers after a single exposure. Bladder is the most frequent organ involved within the urinary tract, although upper
Andres González, Clara Sánchez Guerrero, Francisco Javier Burgos Revilla, Vital Hevia, Javier Lorca, Victor Diez Nicolás   +5 more
core   +1 more source

Compartment‐Specific Immune Remodeling of Renal Aging With C1q‐Associated Podocyte Activation

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Aging repatterns the renal immune response in a compartment‐specific manner, distinct from chronic kidney disease (CKD) adaptation. Glomerular aging features C1q‐associated podocyte activation and macrophage engagement, whereas tubulointerstitial aging is marked by B‐cell aggregation and tertiary lymphoid structure expansion.
Ju‐Young Moon, Kyuwon Shim, Hyun Ji Lim, Dae‐Kyu Kim, Young Yoon Moon, Su‐Woong Jung, Yang‐Gyun Kim, Hyuno Kang, Tae‐Hoon Lee, Jae‐Hyung Lee, Sang‐Ho Lee   +10 more
wiley   +1 more source

Diagnostic Values of Serum Procalcitonin in Kidney Diseases

, 2015
Many clinical studies have confirmed Procalcitonin (PCT) as a specific inflammatory marker in sepsis and bacterial infections. It is believed that PCT level is increased in various noninfectious conditions such as acute pancreatitis, major surgery ...
Ghafari, Alireza, Mohkam, Masoumeh, Kompani, Farshid   +2 more
core   +1 more source