Results 161 to 170 of about 9,061,852 (330)

Mechanism Analysis of Zuogui and Yougui Pills on Diabetic Nephropathy Through Transcriptional Regulatory Networks of HIF1A and PPARA

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
The shared mechanisms of Zuogui Pill (ZGP) and Yougui Pill (YGP) for treating diabetic nephropathy is HIF1A‐CA9‐PDK1 and PPARA‐PDK4. ZGP and YGP inhibited renal fibrosis and relieved the decrease in glucose consumption through transcriptional regulatory network of HIF1A and PPARA.
Liansheng Qiao, Xiaopeng Zhao, Anlei Yuan, Chaoqun Liu, Zewen Wang, Xiaoqian Huo, Shijie Bi, Jiaye Tian, Bin Yu, Zhaozhou Lin, Yanling Zhang, Jiwang Zhang   +11 more
wiley   +1 more source

Intradiscal Mesenchymal Stromal Cell Therapy for the Treatment of Low Back Pain Due to Moderate‐to‐Advanced Multilevel Disc Degeneration: A Preliminary Report of a Double‐Blind, Phase IIB Randomized Clinical Trial (DREAM Study)

JOR SPINE, Volume 8, Issue 2, June 2025.
This phase IIB randomized controlled trial evaluated the safety and efficacy of intradiscal injections of autologous bone marrow‐derived mesenchymal stromal cells (BM‐MSCs) in patients with chronic low back pain from moderate‐to‐advanced multilevel disc degeneration.
Gianluca Vadalà, Fabrizio Russo, Cristiana Lavazza, Giorgia Petrucci, Luca Ambrosio, Silvia Budelli, Elisa Montelatici, Giuseppina Di Giacomo, Claudia Cicione, Veronica Tilotta, Giuseppe Francesco Papalia, Matteo Pileri, Amalia Bruno, Salvatore La Rosa, Emilio Carrino, Eliodoro Faiella, Massimiliano Carassiti, Lorenza Lazzari, Rocco Papalia, Vincenzo Denaro   +19 more
wiley   +1 more source

Impact of Pelvic Lymph Node Dissection on Early Oncological Outcomes in Intermediate‐Risk Prostate Cancer Patients With Node‐Negative PSMA PET

The Prostate, Volume 85, Issue 8, Page 777-783, June 2025.
ABSTRACT Background PSMA PET/CT has previously shown superior performance in nodal staging of prostate cancer (PCa) and may be used to reduce the number of unnecessary PLND procedures. This study aims to assess the performance of PSMA PET/CT in nodal staging of intermediate‐risk prostate cancer and to evaluate the effect of PLND on oncological outcomes
Baris Esen, Hulya Seymen, Ayşe Armutlu, Ersin Koseoglu, Ibrahim Can Aykanat, Hatice Zoroğlu, Abdullah Erdem Canda, Yakup Kordan, Mevlana Derya Balbay, Dilek Ertoy Baydar, Mehmet Onur Demirkol, Derya Tilki, Tarık Esen   +12 more
wiley   +1 more source

Virtual Reality for Preoperative Planning and Education in Pediatric Surgery: Preliminary Results for the Treatment of Congenital Malformations and Tumors

World Journal of Surgery, Volume 49, Issue 6, Page 1497-1507, June 2025.
Virtual reality (VR) has emerged as a valuable tool in pediatric surgical planning, offering detailed anatomical spatial orientation and three‐dimensional (3D) navigation. ABSTRACT Purpose Virtual reality (VR) has emerged as a valuable tool in surgical planning, offering detailed anatomical spatial orientation and three‐dimensional (3D) navigation ...
Gloria Pelizzo, Ugo Maria Pierucci, Michela Marinaro, Sara Costanzo, Eleonora Durante, Carlotta Ardenghi, Alessia Musitelli, Paolo Milani, Francesco Rizzetto, Maurizio Vertemati, Alessandro Campari, Marta Barisella, Tommaso Santaniello, Cristina Gallotta, Anna Camporesi, Irene Paraboschi, Alessandro Varrica, Daniele Alberti, Valeria Calcaterra, Gianvincenzo Zuccotti   +19 more
wiley   +1 more source

Microbial colonization and ureteral stent-associated storage lower urinary tract symptoms: the forgotten piece of the puzzle? [PDF]

, 2018
Purpose: Ureteral stents are frequently associated with side effects. Most patients suffer from storage lower urinary tract symptoms (LUTS). Storage LUTS are commonly attributed to the irritation of the trigone, smooth muscle spasm or a combination of ...
Bachmann, Alexander, Bonkat, Gernot, Frei, Reno, Gasser, Thomas, Müller, Georg, Rieken, Malte, Roosen, Alexander, Siegel, Fabian, Widmer, Andreas, Wyler, Stephen   +9 more
core  

SMYD2 Promotes Renal Tubular Cell Apoptosis and Chronic Kidney Disease Following Cisplatin Nephrotoxicity

The FASEB Journal, Volume 39, Issue 10, 31 May 2025.
SMYD2 mediates the activation of the NF‐κB signaling pathway to promote cisplatin‐induced chronic kidney injury. Cisplatin stimulation induces the upregulation of SMYD2 expression in renal tubular epithelial cells. SMYD2 promotes the phosphorylation of the p65 subunit of NF‐κB through methylation, thereby facilitating the release of inflammatory ...
Siyang Zuo, Huixiong Yuan, Xia Li, Ming Chen, Rui Peng, Siyu Chen, Xue Zou, Yuan Yang, Hehua Long, Zeying Liu, Teng Wang, Bing Guo, Lirong Liu   +12 more
wiley   +1 more source

Altered ureteral contractility with ageing:Role of the rho-kinase pathway [PDF]

, 2018
Chess-Williams, Russ, Lim, Iris, Sellers, Donna   +2 more
core   +1 more source

Improved detection of microbial ureteral stent colonisation by sonication [PDF]

, 2018
Purpose: The diagnosis of microbial ureteral stent colonisation (MUSC) is difficult, since routine diagnostic techniques do not accurately detect microorganisms embedded in biofilms.
Bonkat, Gernot, Rieken, Malte, Rentsch, Cyrill, Wyler, Stephen, Feike, Antje, Schäfer, Juliane, Gasser, Thomas, Trampuz, Andrej, Bachmann, Alexander, Widmer, Andreas   +9 more
core   +1 more source

Robot-assisted laparoscopic ureteroneocystostomy in adults: A single surgeon experience and literature review

Asian Journal of Urology, 2020
Objective: To present our experience and technique with robot-assisted ureteroneocystostomy (RAUN) procedure in adults. Methods: Between February 2015 and August 2018, a total of 30 (34 ureters) patients who underwent RAUN surgery under a single surgeon ...
Najib Isse Dirie, Shaogang Wang
doaj  

The appendix is a valuable reconstructive tool for robotic surgical management of complex right ureteral stricture disease

, 2020
Raevti Bole, Paige Nichols, Ajay Gopalakrishna, Nicole Dodge, Madeline Manka, Boyd R. Viers   +5 more
openalex   +1 more source