Results 131 to 140 of about 420,744 (320)

High Phosphate Load Induces De Novo Formation of Tertiary Lymphoid Structures in the Kidney

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
Graphical illustration of renal alterations under varying phosphate load: High phosphate load induces fibrosis, tubular injury, impaired renal function, and de novo formation of perivascular tertiary lymphoid structures. Under normal phosphate load, fibrosis, functional decline, and tubular injury are absent, while T‐ and B‐ cell aggregates are present
Nina Weingärtner, Beatrice Richter, Franziska Walles, Tamar Kapanadze, Jessica Schmitz, Jan H. Bräsen, Florian P. Limbourg, Dieter Haffner, Maren Leifheit‐Nestler   +8 more
wiley   +1 more source

VALSARTAN TO ATTENUATE RENAL DAMAGE IN UNILATERAL URETERAL OBSTRUCTION

Jurnal Urologi Indonesia, 2014
Objective: This experimental study aims to observe the effect of valsartan to attenuate renal damage in unilateral ureteral obstruction. Material & method: Experimental study was performed using 30 wistar rats with unilateral ureteral obstruction ...
Samycha Jusuf, Alvarino Alvarino
doaj   +1 more source

SP427UNILATERAL URETERAL OBSTRUCTION-INDUCED KIDNEY FIBROSIS IS EXACERBATED BY DEFICIENCY OF METHIONINE SULFOXIDE REDUCTASE A GENE [PDF]

, 2015
Jee In Kim, Mi Ra Noh, Kwon Moo Park
openalex   +1 more source

Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2+PIRB+ Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis

Advanced Science, Volume 12, Issue 46, December 11, 2025.
The ANGPTL8/PIRB/ALOX5AP axis mediates liver‐kidney crosstalk. Hepatocytes secrete ANGPTL8, which binds to CCR2+PIRB+ macrophages in the kidneys, affecting the expression of ALOX5AP and enhancing the activation of these macrophages. Activated cells produce TGF‐β, IL‐6, and IL‐23, driving Th17 activation and promote the formation of myofibroblasts ...
Shuqi Wei, Diwen Shou, Siyuan Huang, Yingsi Wang, Quanzhen Liu, Jinfa Liu, Xiaoyu Lv, Yuyi Zeng, Liting Wei, Han Lin, Jiechuan Chen, Yangxiao Chen, Haoyu Zhong, Yanqing Zhou, Wen Ma, Li Wang, Guojun Qian, Jing Guo, Donglin Sun   +18 more
wiley   +1 more source

Ureteral Obstruction Due to Inadvertent Placement of the Suprapubic Catheter and Bladder Indwelling Catheter: Presentation of Two Clinical Cases and Review of the Literature [PDF]

, 2022
Victor Calderon Plazarte, Maxime Taghavi, Lucas Jacobs, Johanna Elisabeth Noels   +3 more
openalex   +1 more source

Flexible ureteroscopy with a flexible and navigable suction ureteral access sheath versus mini‐percutaneous nephrolithotomy for 1–2 cm lower pole renal stones: Protocol for an international, multicentre, randomized non‐inferiority trial (FLAME trial)

BJUI Compass, Volume 6, Issue 12, December 2025.
Abstract Background Lower pole renal stones measuring 1–2 cm remain challenging to treat. While mini‐percutaneous nephrolithotomy (mini‐PCNL) provides high stone‐free rates (SFRs), it carries tract‐related morbidity. Flexible ureteroscopy (f‐URS) is less invasive but limited in SFR.
Wei Zhu, Jinghua Zhong, Kefeng Wang, Guangming Yin, Chi‐Ho Leung, Nariman Gadzhiev, Mehmet Ilker Gökce, Jaisukh Kalathia, Vineet Gauhar, Guangyuan Zhang, Gang Wu, Mingyong Li, Li Fang, Shaohua Zeng, Peide Bai, Ji Li, Zhenhua Zhao, Ming Xi, Xin Mai, Xianzhong Duan, Kehua Jiang, Jianwei Cao, Xianghu Meng, Shusheng Liu, Aram Aloyan, Peng Yuan, Xiaorui Zhu, Ting Huang, Jianhui Xing, Jingzeng Du, Wenqi Wu, Jinxiang Ma, Wen Zhong, Zhijian Zhao, Yongda Liu, Chi Fai Ng, Jean de la Rosette, Bhaskar Somani, Shiyong Qi, Guohua Zeng, Steffi Kar Kei Yuen   +40 more
wiley   +1 more source

Analysis of Ureteral Tumour Stents for Malignant Ureteral Obstruction: Towards Reshaping an Optimal Stent

Research and Reports in Urology, 2021
Benoît Vogt,1 Laure-Hélène Blanchet2 1Department of Urology, Polyclinique de Blois, La Chaussée Saint-Victor, 41260, France; 2Department of Public Health, Hôpital Saint-Antoine (AP-HP), Paris, 75012, FranceCorrespondence: Benoît VogtDepartment of Urology,
Vogt B, Blanchet LH
doaj  

Mechanosensitive Piezo1 Channels Mediate Diaphragm Fibrosis Induced by Prolonged Mechanical Ventilation

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Ventilator‐induced diaphragmatic dysfunction (VIDD) is a major complication in critically ill patients. Prolonged mechanical ventilation (MV) triggers diaphragmatic fibrotic remodelling, but the underlying mechanisms remain unclear. This study investigated the role of the mechanosensitive channel Piezo1 in this process.
Dan Xie, Yuru Xiao, Xuexin Li, Bowen Sun, Jianguo Feng, Jing Jia, Jie Li, Yun Wang, Fei He, Li Liu   +9 more
wiley   +1 more source

Mechanical Signaling: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
In this review, we summarize cell–ECM interactions and delve into the complex mechanotransduction. We introduce advanced research methods and emerging clinical tools used to study cellular mechanical phenotypes, mechanotransduction, and disease progression. Additionally, we analyze the role of mechanical biomarkers in the development and progression of
Yicen Long, Peng Wang, Jiacheng Lei, Baihai Su, Qiang Wei, Xiaojing Liu   +5 more
wiley   +1 more source

Current Application Status and Innovative Development of Surgical Robot

Med Research, Volume 1, Issue 3, Page 378-396, December 2025.
Advantage, Challenge and Innovation of surgical robots. ABSTRACT Surgery has undergone a revolutionary development since the innovations in anesthesiology, aseptic techniques, and antibiotics. The use of modern techniques, especially minimally invasive techniques, has led to a new era of microsurgery and reduced patient trauma.
Aimin Jiang, Zhao Tang, Hanzhong Zhang, Jinxin Li, Jialin Meng, Ying Liu, Yu Fang, Juan Lu, Xu Zhang, Le Qu, Anqi Lin, Linhui Wang   +11 more
wiley   +1 more source