Results 111 to 120 of about 63,403 (267)

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

open access: yesPediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou   +10 more
wiley   +1 more source

The Clinical Efficacy of High‐Voltage Long‐Duration Pulsed Radiofrequency Treatment in Pudendal Neuralgia: A Retrospective Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley   +1 more source

A Simple Cell Culture Assay for Human Prostatic Branching Morphogenesis Spotlights Bone Morphogenetic Protein Signaling as a Therapeutic Target in Benign Prostatic Hyperplasia

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) leads to prostate enlargement and lower urinary tract symptoms that can resist treatment. A histologic hallmark of BPH is glandular epithelial hyperplasia with new ductal branching morphogenesis. The stromal inductive factors driving tissue morphogenesis may provide new therapeutic targets, but are
Anna S. Pollack   +2 more
wiley   +1 more source

The Effect of Pessary Insertion on Pelvic Anatomy: A Prospective Observational Study Using Upright MRI

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine the anatomical effect of pessaries in the upright position in women with pelvic organ prolapse (POP). Design Prospective observational cohort study. Setting Outpatient clinic of our gynaecology department. Population Fifteen POP patients with successful ring‐shaped pessary use.
Annemarie van der Steen   +5 more
wiley   +1 more source

Empty Versus Full Bladder Protocols in Radiotherapy Planning for Localised Prostate Cancer: A Dosimetric Study

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background When planning prostate radiotherapy, full bladder preparation is widely used to displace bowel and bladder from high‐dose regions but is difficult to reproduce and can prolong workflows. Methods Twenty men with localised prostate cancer ± seminal vesicles underwent CT simulation with full and empty bladders.
Rebecca Louise Nield   +3 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

Urethral foreign bodies: a hidden consequence of autoerotic behavior-a case report. [PDF]

open access: yesJ Med Case Rep
Albaddai N   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy