Results 51 to 60 of about 9,389,752 (328)

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

The Etiology of Male Urethral Discharge in Zimbabwe: Results from the Zimbabwe STI Etiology Study

Sexually Transmitted Diseases, 2017
Introduction Sexually transmitted infections (STIs) are managed syndromically in most developing countries. In Zimbabwe, men presenting with urethral discharge are treated with a single intramuscular dose of kanamycin or ceftriaxone in combination with a
C. Rietmeijer, M. Mungati, A. Machiha, O. Mugurungi, V. Kupara, Luanne Rodgers, P. Kilmarx, A. Roloff, E. Gonese, Beth A. Tippett-Barr, Gerald Shambira, D. Lewis, H. Handsfield, M. Tshimanga   +13 more
semanticscholar   +1 more source

Surgical treatment of urethral stricture disease – the earlier, the better [PDF]

, 2021
Valeri Mariyanovski, Emil Dorosiev, Boris Mladenov   +2 more
openalex   +1 more source

Risk Factors for Anastomotic Stricture and Obstructive Symptoms Following Double‐Flap Technique Reconstruction After Proximal Gastrectomy

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study investigated risk factors for anastomotic stricture and obstructive symptoms following double‐flap technique (DFT) reconstruction after proximal gastrectomy. Mucosal detachment, potentially caused by thermal damage, was identified as a significant risk factor for anastomotic stricture, while continuous suturing at the esophago ...
Shinji Kuroda, Yoshihiko Kakiuchi, Satoru Kikuchi, Hajime Kashima, Nobuhiko Kanaya, Shunya Hanzawa, Kenjiro Kumano, Masahiko Nishizaki, Shunsuke Kagawa, Toshiyoshi Fujiwara   +9 more
wiley   +1 more source

Changing Concept of Urethral Stricture Disease

Apollo Medicine, 2009
Urethral strictures was always a challenging disease for the urologist and fight to find a ideal and perfect operation is still not over. However in last 20 years newer concepts have evolved which has vastly improved the outcome. End to end urethroplasty and buccal mucosal substitution urethroplasty have become more common operation.
Ritesh Mongha, Anant Kumar
openaire   +1 more source

Female Urethral Disease: A Contemporary Review of Presentation, Diagnosis and Current Management Strategies [PDF]

, 2021
Cope Z, Carlita Anglin, Adam Dryden, Jenci Hawthorne, Choi KBY   +4 more
openalex   +1 more source

Impact of Abdominoperineal Resection on Postoperative Male Sexual Function After Minimally Invasive Rectal Cancer Surgery: A Subgroup Analysis From the LANDMARC Study

Annals of Gastroenterological Surgery, EarlyView.
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara, Shinobu Ohnuma, Michiaki Unno, Masakatsu Numata, Tomohiro Yamaguchi, Koya Hida, Tomonori Akagi, Suguru Hasegawa, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Keisuke Kazama, Masanori Hotchi, Masahiko Watanabe, Takeshi Naitoh   +14 more
wiley   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Comparison of Effectiveness between Tension-Free Vaginal Tape (TVT) and Trans-Obturator Tape (TOT) in Patients with Stress Urinary Incontinence and Intrinsic Sphincter Deficiency. [PDF]

PLoS ONE, 2016
The aim of this study was to compare the two types of mid-urethral slings for stress urinary incontinence (SUI) with intrinsic sphincter deficiency (ISD).This retrospective study included patients who underwent tension-free vaginal tape (TVT) procedure ...
Hyeong Gon Kim, Hyoung Keun Park, Sung Hyun Paick, Woo Suk Choi   +3 more
doaj   +1 more source

Urethral stricture disease: Measuring success in treatment [PDF]

Canadian Urological Association Journal, 2012
Urethral stricture disease and its management are complex. The UREThRAL stricture score (USS) as described by Wiegand and Brandes is a novel method to describe and quantify urethral stricture disease.1 To develop the USS, they chose factors they believed to be important and assigned a point value to each domain.
openaire   +3 more sources