Results 111 to 120 of about 352,025 (244)

Mosaic KRAS Mutation in Schimmelpenning–Feuerstein–Mims Syndrome With Overlapping Oculoectodermal Syndrome and Encephalocraniocutaneous Lipomatosis Features

Pediatric Dermatology, EarlyView.
ABSTRACT We report a patient with clinically confirmed Schimmelpenning–Feuerstein–Mims (SFM) syndrome but many overlapping features with oculoectodermal syndrome (OES) and encephalocraniocutaneous lipomatosis (ECCL). Whole exome sequencing revealed a mosaic KRAS c.436G>A, p.(Ala146Thr) mutation, previously identified in three OES and ECCL patients ...
Hyvönen Hanna, Kettunen Kaisa, Avela Kristiina, Kivirikko Sirpa, Jeskanen Leila, Suominen Sinikka, Salminen Päivi, Hannula‐Jouppi Katariina   +7 more
wiley   +1 more source

Characterisation of Gene Expression in Canine Invasive Urothelial Carcinoma Using a NanoString‐Based Urine Assay

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT For human and canine invasive urothelial carcinoma (InvUC), there is growing interest in using the molecular characteristics of a tumour to guide individualised treatment strategies. The objective of this study was to use a non‐invasive, urine‐based method to characterise gene expression signatures in dogs with InvUC.
Ellen Marie Kuerbitz, Deepika Dhawan, Sagar Utturkar, Mario Francis Sola, Alexander William Enstrom, Lindsey Marie Fourez, Deborah Wagner Knapp   +6 more
wiley   +1 more source

Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography–tandem mass spectrometry

Veterinary Clinical Pathology, EarlyView.
Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey, P. R. Antrobus, T. L. Williams   +2 more
wiley   +1 more source

Metastatic Sites in Rare Genitourinary Malignancies and Primary Cancer Sites in Genitourinary Organ Metastases: A Secondary Analysis Using the Japanese Pathological Autopsy Registry Database

European Urology Open Science
Background: The epidemiology of metastases from rare genitourinary cancer and metastases to genitourinary organs from other primary neoplasms remains poorly understood. Objective: To investigate the epidemiology of rare genitourinary metastases from rare
Suguru Oka, Tomohiko Hara, Shinji Ito, Michikata Hayashida, Kazushige Sakaguchi, Shinji Urakami   +5 more
doaj  

Performance of a large language model-Artificial Intelligence based chatbot for counseling patients with sexually transmitted infections and genital diseases [PDF]

arXiv
Introduction: Global burden of sexually transmitted infections (STIs) is rising out of proportion to specialists. Current chatbots like ChatGPT are not tailored for handling STI-related concerns out of the box. We developed Otiz, an Artificial Intelligence-based (AI-based) chatbot platform designed specifically for STI detection and counseling, and ...
arxiv  

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Propensity Score Matched Analysis of External Beam Radiotherapy With or Without Focal Boost to Intraprostatic Lesions in Prostate Cancer

The Prostate, Volume 85, Issue 8, Page 805-813, June 2025.
ABSTRACT Background This study evaluated the impact of radiotherapy (RT) with or without a simultaneous integrated boost (SIB) to intraprostatic lesions on survival, recurrence, and toxicity in localized prostate cancer (PCa). Key prognostic and predictive factors were also analyzed.
Cem Onal, Ozan Cem Guler, Gurcan Erbay, Birhan Demirhan, Aysenur Elmali, Melek Yavuz   +5 more
wiley   +1 more source

Risk of upper urinary tract urothelial carcinoma after primary non‐muscle‐invasive urinary bladder cancer: A nationwide population‐based cohort study

BJUI Compass, Volume 6, Issue 5, May 2025.
Abstract Objectives To investigate the risk of upper urinary tract urothelial carcinoma (UTUC) in patients with non‐muscle‐invasive bladder cancer (NMIBC), in relation to the primary NMIBC tumour risk categories, calendar time trends and intravesical Bacillus Calmette‐Guerin (BCG) treatment. Patient and methods All patients with primary NMIBC diagnosed
Christel Häggström, Oskar Hagberg, Lars Holmberg, Abolfazl Hosseini, Tomas Jerlström, Viveka Ströck, Karin Söderkvist, Anders Ullén, Fredrik Liedberg, Staffan Jahnson, Firas Aljabery   +10 more
wiley   +1 more source

Adverse Outcome of a Solitary Fibrous Tumor Originating in the Bladder

IJU Case Reports, Volume 8, Issue 3, Page 231-235, May 2025.
ABSTRACT Introduction Solitary fibrous tumors originating in the bladder are extremely rare. While generally associated with favorable outcomes, some show invasive behavior. We report a case of a solitary fibrous tumor originating in the bladder that was treated with multimodal therapy.
Takato Nishino, Masaki Shimbo, Eri Fukagawa, Kazutaka Narimoto, Jun Hashimoto, Shin Ogita, Naoki Kanomata, Kazunori Hattori, Fumiyasu Endo   +8 more
wiley   +1 more source

A Case of Penile Cavernosal Abscess Associated With Sigmoid Colovesical Fistula

IJU Case Reports, Volume 8, Issue 3, Page 240-243, May 2025.
ABSTRACT Introduction A penile cavernosal abscess is rare and typically attributable to sepsis, trauma, or intracavernosal injections. Case Presentation A 65‐year‐old man with suspicion of non‐muscle invasive bladder cancer underwent transurethral resection. Edematous and erythematous mucosa was noted on the posterior wall.
Kazuto Imai, Kanji Nagahama, Norihiko Masuda, Takashi Ito, Takakazu Matsushita, Toshiya Akao   +5 more
wiley   +1 more source