Results 91 to 100 of about 173,447 (265)

Diagnostic Yield of Post‐Mortem Fetal Micro‐CT for Abdominal and Pelvic Anomalies

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective(s) This study aims to document the abdominal and pelvic anomalies that can be demonstrated using post mortem Micro‐CT, independent of whether the anomaly contributed to the main diagnosis or cause of death. Methods We retrospectively analyzed 1200 whole body post‐mortem fetal Micro‐CT scans in an unselected, consecutive cohort ...
Ian C. Simcock, Audrey Lamouroux, Susan C. Shelmerdine, J. Ciaran Hutchinson, Neil J. Sebire, Owen J. Arthurs   +5 more
wiley   +1 more source

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Treatment of urethral obstruction secondary to caudal bladder displacement, trigonal invagination, and urethral kinking in a dog

, 2017
CASE DESCRIPTION A 15-year-old spayed female mixed-breed dog was evaluated for a 7-week history of stranguria, pollakiuria, and intermittent urethral obstruction. CLINICAL FINDINGS On initial evaluation, the patient had persistent stranguria with lack of
Kayo Kanakubo, Carrie A. Palm, William T. N. Culp, Amber L. Korner   +3 more
core   +1 more source

Protective Effects Induced by a Novel Food Supplement Based on Epilobium angustifolium, Ptychopetalum olacoides, Ginkgo biloba, and Equisetum arvense Extracts and Citrulline in the Lower Urinary Tract: Preclinical and Clinical Evidence

Phytotherapy Research, EarlyView.
ABSTRACT Oxyfil is a dietary supplement including plant extracts from Epilobium angustifolium, Ptychopetalum olacoides (Muira puama), Ginkgo biloba, and Equisetum arvense and citrulline. The aim of the study was to investigate the protective effects on prostatic muscles of the Oxyfil formulation in an in vitro experimental model consisting of isolated ...
Annalisa Chiavaroli, Alessandra Acquaviva, Simonetta Cristina Di Simone, Stefano Salvatore, Silvia Messina, Carolina Morgante, Chiara Lupi, Silvia Villa, Gokhan Zengin, Giustino Orlando, Luigi Menghini, Claudio Ferrante, Luigi Schips, Luca Cindolo, Michele Marchioni   +14 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Urinary retention from urethral calculi in a child with hypospadias

Urology Case Reports
Urethral calculi are rare. They are often related to urinary obstruction, neurogenic bladder, or other anatomical variations. This report describes a four-year-old male with urethral calculi secondary to hypospadias and complicated by intermittent ...
Gilad A. Hampel, Faizan Khawaja, Douglas Coplen, Hubert Swana   +3 more
doaj   +1 more source

Spectrum of Congenital Malformations in Sex Chromosome Tetrasomies and Pentasomies: A Systematic Review

Andrology, EarlyView.
ABSTRACT Sex chromosome aneuploidies represent a heterogeneous group of chromosomal conditions, in which phenotypic complexity generally increases with the number of supernumerary sex chromosomes. While Turner syndrome and sex chromosome trisomies are relatively well characterized, less is known about congenital malformations in sex chromosome ...
Anna Colding, Jannie Traberg, Inger Lily Hjuler Dorf, Anne Skakkebæk   +3 more
wiley   +1 more source

Nursing a patient with feline urethral obstruction

Feline urethral obstruction is a potentially life-threatening condition. The maintenance and monitoring of the patient's electrolyte levels and fluid balance, and urinary catheter management, as well as an individual nursing care plan is vital for a ...
Mistry, Krishna, O'Byrne, Evelyn
core   +1 more source

Robot‐Assisted Peritoneal Flap Vaginoplasty Versus Penile Inversion Vaginoplasty for Gender Affirming Surgery

Andrology, EarlyView.
ABSTRACT Background Direct comparison of robot‐assisted peritoneal flap (PF) to penile inversion (PI) vaginoplasty for gender affirming surgery is absent. Objectives We sought to compare these two techniques to aid patient decision‐making. Materials and Methods A retrospective case–control study of patients who underwent primary PI (N = 40) or PF (N ...
Chantal J. Allan, Michaela Sljivich, Dan Kahan, Camille Torres, Michael Palese, Miroslav Djordjevic, Rajveer S. Purohit   +6 more
wiley   +1 more source