Results 21 to 30 of about 10,532 (169)

A canine model of reversible urethral sphincter insufficiency. [PDF]

Animal Model Exp Med
This study developed an animal model with internal and external urethral sphincter insufficiency by bypassing the sphincter without major damage so that the animal under study can return to normal life after the study.
Shokri P, Tabatabaei S, Ziaee SAM, Pedram MS, Dehghan MM, Shakhssalim N.   +5 more
europepmc   +2 more sources

Therapeutic Effects of Botulinum Toxin A, via Urethral Sphincter Injection on Voiding Dysfunction Due to Different Bladder and Urethral Sphincter Dysfunctions. [PDF]

Toxins (Basel), 2019
Botulinum toxin A (BoNT-A) urethral sphincter injections have been applied in treating voiding dysfunction but the treatment outcome is not consistent. This study analyzed treatment outcomes between patients with different bladder and urethral sphincter ...
Lee YK, Kuo HC.
europepmc   +2 more sources

Efficacy of Urethral Sphincter Botulinum Toxin A Injection in Patients with Spinal Cord Injury with Dysuria: A Retrospective Cohort Study. [PDF]

Toxins (Basel)
Spinal cord injury (SCI) often leads to neurogenic lower urinary tract dysfunction, causing dysuria and affecting patients’ well-being. This study aimed to evaluate the efficacy of a urethral sphincter botulinum toxin A (BoNT-A) injection in patients ...
Yu WR, Tian JH, Kuo HC.
europepmc   +2 more sources

Human primary muscle stem cells regenerate injured urethral sphincter in athymic rats. [PDF]

Animal Model Exp Med, 2022
Background The aim of the study was to demonstrate the efficacy of human muscle stem cells (MuSCs) isolated using innovative technology in restoring internal urinary sphincter function in a preclinical animal model.
Bekele BM, Schöwel-Wolf V, Kieshauer J, Marg A, Busjahn A, Davis S, Nugent G, Ebert AK, Spuler S.   +8 more
europepmc   +2 more sources

Site-Specific Neuromodulation of Detrusor and External Urethral Sphincter by Epidural Spinal Cord Stimulation. [PDF]

Front Syst Neurosci, 2020
Impairments of the lower urinary tract function including urine storage and voiding are widely spread among patients with spinal cord injuries. The management of such patients includes bladder catheterization, surgical and pharmacological approaches ...
Sysoev Y, Bazhenova E, Lyakhovetskii V, Kovalev G, Shkorbatova P, Islamova R, Pavlova N, Gorskii O, Merkulyeva N, Shkarupa D, Musienko P.   +10 more
europepmc   +2 more sources

What do we really know about the external urethral sphincter?

Continence (Amst)
The external urethral sphincter (EUS), composed of skeletal muscle, along with a smooth muscle-lined internal urethral sphincter (IUS), have crucial roles in maintaining continence during bladder filling and facilitating urine flow during voiding ...
McCloskey KD, Kanai A, Panicker JN, Hashitani H, Fry CH.   +4 more
europepmc   +2 more sources

Placement of an artificial urethral sphincter in 8 male dogs with urethral diverticulum. [PDF]

J Vet Intern Med
Background Urethral diverticulum (UD) is a poorly defined anomaly consisting of an outpouching of the urethra. Management without surgical resection is not previously reported in dogs.
Neumann G, Vachon C, Culp WTN, Palm C, Byron JK, Pogue J, Dunn M.   +6 more
europepmc   +2 more sources

The Outcome of Cell Therapy Treating Urinary Incontinence Correlates with Precise Cell Localization in the Sphincter Complex. [PDF]

Biomedicines
Background/Objectives: Urethral sphincter muscle deficiency is the leading cause of stress urinary incontinence. Preclinical and clinical studies suggested that cell therapy may improve the situation.
Harland N, Johnen L, Avula KT, Buzanich-Ladinig A, Schwarz L, Knoll J, Stenzl A, Aicher WK.   +7 more
europepmc   +2 more sources

Single piece artificial urinary sphincter for secondary incontinence following successful repair of post traumatic urethral injury

Journal of Indian Association of Pediatric Surgeons, 2013
Post traumatic urethral injury is uncommon in children. The management of this condition is dependent on the severity of injury. Initial suprapubic cystostomy with delayed repair is the conventional treatment. Successful reconstruction of urethral injury
D K Kandpal, S K Rawat, S Kanwar, A Baruha, S K Chowdhary   +4 more
doaj   +2 more sources

Changes in urethral smooth muscle and external urethral sphincter function with age in rats. [PDF]

Physiol Rep, 2021
Oshiro T, Kimura R, Izumi K, Ashikari A, Saito S, Miyazato M.   +5 more
europepmc   +3 more sources