Results 31 to 40 of about 141,973 (307)

Open urethroplasty versus endoscopic urethrotomy - clarifying the management of men with recurrent urethral stricture (the OPEN trial) : study protocol for a randomised controlled trial [PDF]

, 2015
Peer reviewedPublisher ...
Barclay, Stewart, Brown, Robbie, Carnell, Sonya, Cook, Jonathan A, Goulao, Beatriz, Jackson, Matthew, Johnson, Nicola, MacLennan, Graeme, McColl, Elaine, McPherson, Gladys, Mundy, Anthony, N'Dow, James, Norrie, John, Payne, Steven, Pickard, Robert, Rapley, Tim, Rees, Rowland, Shen, Jing, Sinclair, Andrew, Stephenson, Rachel, Vale, Luke, Watkin, Nick, Wilkinson, Jennifer   +22 more
core   +4 more sources

Significance of inflammatory biomarkers and urethral histology in patients with urethral stricture disease in relation to treatment outcome—a single centre prospective study in the north-eastern part of India

African Journal of Urology, 2022
Background Inflammation plays a very important role in defining the urethral stricture. Inflammatory biomarkers may play an important role in predicting the underlying pathophysiology as well as outcome of surgery.
Nikhil Saurabh
doaj   +1 more source

Synchronous genitourinary lichen sclerosus signals a distinct urinary microbiome profile in men with urethral stricture disease. [PDF]

, 2021
PurposeAlterations in the urinary microbiome have been associated with urological diseases. The microbiome of patients with urethral stricture disease (USD) remains unknown.
Breyer, Benjamin N, Castellanos, Erick R, Cohen, Andrew J, Enriquez, Anthony, Fadrosh, Douglas, Fergus, Kirkpatrick B, Gaither, Thomas W, Lynch, Susan, Mmonu, Nnenaya A, Srirangapatanam, Sudarshan   +9 more
core   +1 more source

Perineal urethrostomy: surgical and functional evaluation of two techniques [PDF]

, 2015
Introduction. PU is an option to manage complex and/or recurrent urethral strictures and is necessary after urethrectomy and/or penectomy. PU is generally assumed to be the last option before abandoning the urethral outlet. Methods. Between 2001 and 2013,
Beysens, Matthias, Decaestecker, Karel, Hoebeke, Piet, Lumen, Nicolaas, Oosterlinck, Willem, Spinoit, Anne-Françoise, Van Praet, Charles   +6 more
core   +3 more sources

Canadian Urological Association guideline on male urethral stricture.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020
Urethral stricture is fundamentally a fibrosis of the urethral epithelial and associated corpus spongiosum, which in turn, causes obstruction of the urethral lumen. Patients with urethral stricture most commonly present with lower urinary tract symptoms,
K. Rourke, B. Welk, R. Kodama, G. Bailly, T. Davies, N. Santesso, P. Violette   +6 more
semanticscholar   +1 more source

Development of male and female models of long urethral strictures in swine

Surgery Open Science, 2023
Background: Preclinical animal models which mimic the dimensions of long urethral strictures (>2 cm in length) encountered in the clinic are necessary to evaluate prospective graft designs for urethroplasty.
Gokhan Gundogdu, MD, Travis Nguyen, BSc, Mando Eijansantos, BSc, Ambika Chaudhuri, BSc, David Barham, MD, Joel Gelman, MD, Joshua R. Mauney, PhD   +6 more
doaj   +1 more source

A drug-coated balloon treatment for urethral stricture disease: Two-year results from the ROBUST I study.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020
INTRODUCTION Mechanical balloon dilation and direct visualization internal urethrotomy (DVIU) are the most widely used treatments for urethral stricture disease in the U.S., but recurrence rates are high, especially after re-treatment.
Rachel Mann, R. Virasoro, J. DeLong, R. Estrella, M. Pichardo, R. R. Lay, G. Espino, J. Roth, S. Elliott   +8 more
semanticscholar   +1 more source

A drug-coated balloon treatment for urethral stricture disease: Interim results from the ROBUST I study.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020
INTRODUCTION We aimed to investigate the safety and preliminary efficacy of the Optilume™ paclitaxel-coated balloon for the treatment of recurrent urethral stricture.
R. Virasoro, J. DeLong, Rachel Mann, R. Estrella, M. Pichardo, R. R. Lay, G. Espino, J. Roth, S. Elliott   +8 more
semanticscholar   +1 more source

Revision of perineal urethrostomy using a meshed split-thickness skin graft [PDF]

, 2014
Perineal urethrostomy is considered to be the last option to restore voiding in complex/recurrent urethral stricture disease. It is also a necessary procedure after penectomy or urethrectomy.
Hoebeke, Piet, HOUTMEYERS, PHILIPPE, Lumen, Nicolaas, Monstrey, Stan, Oosterlinck, Willem, Spinoit, Anne-Françoise   +5 more
core   +2 more sources

Extracellular matrix stiffness aggravates urethral stricture through Igfbp3/Smad pathway

Scientific Reports, 2023
Urethral stricture refers to the narrowing of the urethral lumen. While previous studies have hinted at inflammation as the initial driver of this condition, the reasons and mechanisms behind its progression remain largely unknown.
Kaixuan Li, Ke Ding, Quan Zhu, Feng Han, Xi He, Shuo Tan, Ziqiang Wu, Zhihuan Zheng, Zhengyan Tang, Yanling Liu   +9 more
doaj   +1 more source