Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
From soluble uric acid to sodium urate crystal: immune metabolic inflammation driven by uric acid morphological transformation and mechanism-oriented therapy. [PDF]
Yang Q +8 more
europepmc +1 more source
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja +3 more
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Serum albumin and uric acid: biomarkers of neurocognitive and physical function in early Parkinson's disease. [PDF]
Chang CL, Lin TK, Tsai CL.
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Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao +8 more
wiley +1 more source
Uric Acid Variability Is Associated with Poor Prognosis in Heart Failure. [PDF]
Copeland V +9 more
europepmc +1 more source
Gout in pregnancy: Obstetric and neonatal outcomes
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar +3 more
wiley +1 more source
Mediating effect of serum lipids on the BMI-uric acid association: A cross-sectional study. [PDF]
Zhou C, Ma J, Zang C, Tang J, Liang Z.
europepmc +1 more source
Second‐trimester multimetabolite panel for early preeclampsia rule‐out
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins +7 more
wiley +1 more source
Association among serum uric acid, hyperactivity, impulsivity and dietary components in adults: a cross-sectional study Uric acid, hyperactivity/impulsivity symptoms, and dietary components in adults. [PDF]
Molina-Campuzano RA +8 more
europepmc +1 more source

