Results 211 to 220 of about 126,321 (267)

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy. [PDF]

Chempluschem
Hilber S, Attionu SK, Dayie TK, Kreutz C.   +3 more
europepmc   +1 more source

Entabolons: How Metabolites Modify the Biochemical Function of Proteins and Cause the Correlated Behavior of Proteins in Pathways. [PDF]

J Chem Inf Model
Skolnick J, Srinivasan B, Skolnick S, Edelman B, Zhou H.   +4 more
europepmc   +1 more source

Dihydropyrimidine enzyme activity and its effect on chemotherapy toxicity: importance of genetic testing. [PDF]

Cancer Chemother Pharmacol
Shamaei Zadeh A, Roberts D, Williams A, Pandey D, Villano JL.   +4 more
europepmc   +1 more source

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Uridyl Transferases and the Formation of Uridine Triphosphate: Enzymic Production of Uridine Triphosphate: Uridine Diphosphoglucose Pyrophosphorolysis

Nature, 1953
Uridyl Transferases and the Formation of Uridine Triphosphate: Enzymic Production of Uridine Triphosphate: Uridine Diphosphoglucose ...
A, MUNCH-PETERSEN, H M, KALCKAR, E, CUTOLO, E E, SMITH   +3 more
openaire   +3 more sources

Mechanisms of coronary artery depolarization by uridine triphosphate

American Journal of Physiology-Heart and Circulatory Physiology, 2001
We sought to define the basic mechanisms by which pyrimidine nucleotides constrict rat coronary resistance arteries. Uridine triphosphate (UTP) caused a dose-dependent constriction in coronary arteries stripped of endothelium. UTP also depolarized and increased cytosolic Ca2+in coronary smooth muscle cells.
D G, Welsh, J E, Brayden
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Feedback onhibition of uridine kinase by cytidine triphosphate and uridine triphosphate

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1964
Abstract Uridine kinase was found to be the rate-limiting step in the anabolism of uridine to its successive nucleotide derivatives. This enzymatic activity was susceptible to feedback inhibition by the pyrimidine nucleoside triphosphate end-products; effective inhibition was exerted by UTP and even more strikingly by CTP.
E P, ANDERSON, R W, BROCKMAN
openaire   +3 more sources

Extracellular Uridine Triphosphate and Adenosine Triphosphate Attenuate Endothelial Inflammation through miR-22-Mediated ICAM-1 Inhibition

Journal of Vascular Research, 2015
Adenosine and uridine triphosphate (ATP and UTP) can act as extracellular signalling molecules, playing important roles in vascular biology and disease. ATP and UTP acting via the P2Y₂-receptor have, for example, been shown to regulate endothelial dilatation, inflammation and angiogenesis.
Olof Gidlöf, Ramasri Sathanoori, Marco Magistri, Mohammad Ali Faghihi, Claes Wahlestedt, Björn Olde, David Erlinge   +6 more
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Uridine triphosphate (UTP) is released during cardiac ischemia

International Journal of Cardiology, 2005
Extracellular uridine triphosphate (UTP) stimulates vasodilatation, automaticity in ventricular myocytes and release of tissue-plasminogen activator (t-PA), indicating that UTP may be important in cardiac regulation. We took advantage of a recently developed quantitative assay for UTP to test the hypothesis that UTP is released in the circulation ...
David, Erlinge, Jan, Harnek, Catharina, van Heusden, Göran, Olivecrona, Sverker, Jern, Eduardo, Lazarowski   +5 more
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Secretion of ATP from Schwann cells in response to uridine triphosphate

European Journal of Neuroscience, 2005
AbstractThe mechanisms by which uridine triphosphate (UTP) stimulates ATP release from Schwann cells cultured from the sciatic nerve were investigated using online bioluminescence techniques. UTP, a P2Y2 and P2Y4 receptor agonist, stimulated ATP release from Schwann cells in a dose‐dependent manner with an ED50 of 0.24 µm.
Guo Jun, Liu, Eryn L, Werry, Max R, Bennett   +2 more
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Uridine triphosphate and RNA synthesis during diabetes-induced renal growth

American Journal of Physiology-Endocrinology and Metabolism, 1980
UTP, CTP, and RNA synthesis were studied in the renal cortex of diabetic and control rats in vivo. The incorporation of UTP into RNA (nmol/h DNA) was used as estimate of RNA synthesis rate. Two to three days after streptozotocin injection, UTP and CTP ppol size and orotate incorporation into UTP and RNA were greater in diabetic animals than in controls.
P, Cortes, N W, Levin, F, Dumler, A H, Rubenstein, C P, Verghese, K K, Venkatachalam   +5 more
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