Results 31 to 40 of about 60,013 (197)

Robot‐Assisted Laparoscopic Radical Nephrectomy in a Renal Cell Carcinoma Patient With Severe Scoliosis: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction Laparoscopic nephrectomy in patients with severe scoliosis presents significant challenges due to altered anatomy and limited space. This case report discusses using robot‐assisted laparoscopic radical nephrectomy in such a scenario. Case Presentation A 68‐year‐old man with severe right convex scoliosis was diagnosed with cT3aN0M0
Tatsuya Kawamura, Daiki Ikarashi, Ayato Ito, Ei Shiomi, Shigekatsu Maekawa, Renpei Kato, Mitsugu Kanehira, Ryo Takata, Wataru Obara   +8 more
wiley   +1 more source

A multi‐centered prospective birth cohort study in Western China

iMeta, EarlyView.
The Western China Birth Cohort (WCBC) is a large‐scale, multi‐centered, prospective birth cohort study designed to address critical gaps in maternal and child health research in Western China, a region with diverse altitudes, ethnic groups, and unique environmental exposures. WCBC had enrolled 15,093 pregnant women across eight clinical centers in five
Xiangyu Li, Ying Wu, Bin Yi, Mengjie Chen, Gang Zhang, Xiaoshan Shao, Xiulian Jiang, Yuxia Cui, Li Chen, Xiaojing Dong, Shu Zhang, Yao Zhao, Yuebi Deng, Xueqi Li, Yang Wang, Lei Wu, Yu Fu, Dan Ran, Chen Peng, Xiao Yang, Lan Zhang, Yanxia Wang, Yi Zhu, Dina Sun, Yuchen Ran, Dan Zheng, Xuan Yin, Yufen Chen, Yu Long, Wenjing Wang, Xiaodong Zhao, Enmei Liu, Tao Xu, Qiu Li, Wen Zhong   +34 more
wiley   +1 more source

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

Journal of Applied Toxicology, EarlyView.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz, Shira Paz, Rotem Saban, Inbar Zuker, Hagay Shmuely, Katy Gorshkov, Jwar Meetro, Shahrzad Tafazoli, Trung Vo, Gabriela Amiram, Carmit Shani Levi, Uri Lesmes, Ilan Samish   +12 more
wiley   +1 more source

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez, Zhao Yang, William Schelman, Thomas C. Marbury, Juan C. Rondon, William Smith, Xiaofei Zhou, Neeraj Gupta, Caly Chien   +8 more
wiley   +1 more source

Epidermolysis bullosa for primary care providers: A practical review

Journal of General and Family Medicine, EarlyView.
Abstract Epidermolysis bullosa (EB) is a group of genetic skin diseases, which manifest as fragile skin and blistering in addition to many extracutaneous conditions. Pediatricians and primary care providers play an integral role in managing these patients with multifaceted care needs.
Kennedy Sparling, Judith O'Haver, Muayad Shahin, Amanda Damon, Nichole Halliburton, Kellie Badger, Mariam Iqneibi, Beth Moeves, Harper N. Price, Emily S. Gorell   +9 more
wiley   +1 more source

Evaluating antimicrobial effectiveness in acute uncomplicated cystitis: A retrospective single‐center study

Journal of General and Family Medicine, EarlyView.
Abstract Background Acute uncomplicated cystitis (AUC) is a urinary tract infection and is generally treated using antimicrobial therapy. Escherichia coli is the main causative agent of AUC. Recently, the prevalence of fluoroquinolone (FQ)‐resistant‐E. coli has demonstrated a noticeable increase. In this study, we aimed to investigate the effectiveness
Takuhisa Nukaya, Kiyohito Ishikawa, Ryoichi Shiroki   +2 more
wiley   +1 more source

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

Genital Crohn's disease in pediatrics and genetic associations

JPGN Reports, EarlyView.
Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang, Caroline Chinchilla Putzeys, Edward Hoffenberg, Ashish Patel, Elizabeth Hilow, Brad Pasternak   +5 more
wiley   +1 more source

Evaluating Cost‐Effective Strategies for Asymptomatic Microhematuria Diagnosis: A Risk‐Based Alternative to the American Urological Association Guidelines

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives The American Urological Association (AUA) guidelines recommend evaluating asymptomatic microhematuria (MH) at ≥ 3 red blood cells per high powered field (RBCs/hpf), resulting in significant costs with limited bladder cancer detections.
Krishay Sridalla, Hiten D. Patel, Dustin D. French, Joshua J. Meeks, Lili Zhao, Yuying Xing, David J. Bentrem   +6 more
wiley   +1 more source