Results 51 to 60 of about 106,421 (289)

Discharge after acute kidney injury : recognising and managing risk [PDF]

open access: yes, 2016
Peer reviewedPublisher ...
Black, Corri   +2 more
core  

Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang   +5 more
wiley   +1 more source

Pre-eclampsia toxaemia [PDF]

open access: yes, 2013
A 33 year old primagravida rhesus positive woman was referred to the Emergency Department by her family doctor at 27 weeks gestation. At 25 weeks of gestation, she had been diagnosed with hypertension and was started on labetalol therapy.
Bugeja, Roberta, Galdes, Caroline
core  

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]

open access: yes, 2014
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad   +6 more
core   +2 more sources

Enhanced Vatiquinone Bioavailability With Fatty Meals and Optimal Dosing Schedule

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
This investigation discusses two clinical studies. One investigated the effect of fatty meals (≥ 25% fat) on vatiquinone PK exposures, and the other one characterized vatiquinone PK profiles when administered on a TID dosing regimen corresponding to mealtimes. The data support the recommendation of administering vatiquinone with fatty meals (≥ 25% fat)
Lucy Lee   +6 more
wiley   +1 more source

Efficacy and safety of combining bevacizumab and fractionated stereotactic radiotherapy for extensive brain metastases in patients with non‐small cell lung cancer: a prospective phase II study (GASTO‐1053)

open access: yesCancer Communications, EarlyView.
Abstract Background The prognosis for non‐small cell lung cancer (NSCLC) patients with extensive brain metastases (BMs) treated with radiotherapy alone remains poor. Based on the synergistic potential of radiotherapy and angiogenesis inhibitors, we initiated this phase II study to assess the efficacy and safety of combining bevacizumab (Bev) with ...
Rui Zhou   +16 more
wiley   +1 more source

Transient acquired Fanconi syndrome with unusual and rare aetiologies: A case study of two dogs

open access: yesVeterinární Medicína, 2020
The acquired form of Fanconi syndrome is seldom identified in dogs; those cases that have been reported have been secondary to hepatic copper toxicosis, primary hypoparathyroidism, ingestion of chicken jerky treats, exposure to ethylene glycol, or ...
Ju-Yong Park   +3 more
doaj   +1 more source

Electrochemical N-Acetyl-β-D-glucosaminidase Urinalysis: Toward Sensor Chip-Based Diagnostics of Kidney Malfunction

open access: yesBiomolecules, 2021
N-Acetyl-β-D-glucosaminidase (GlcNAcase) is a valuable biomarker for kidney health, as an increased urinary level of the enzyme indicates cell damage within the renal tubular filtration system from acute or chronic organ injury or exposure to nephrotoxic
Piyanuch Vibulcharoenkitja   +2 more
doaj   +1 more source

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