Results 51 to 60 of about 84,269 (340)

Influencing Factors on the Oncuria™ Urinalysis Assay: An Experimental Model

open access: yesDiagnostics, 2021
Background: The Oncuria™ urine test for the detection of bladder cancer measures a multiplex protein signature. In this study, we investigated the influence of urinary cellularity, protein, and hematuria on the performance of the Oncuria™ test in an ex ...
Kaoru Murakami   +6 more
doaj   +1 more source

Evaluation of Potential Effects of CYP3A Inhibition and CYP3A Induction on the Pharmacokinetics of Fruquintinib in Healthy Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Cytochrome P450 (CYP) 3A plays a significant role in fruquintinib metabolism in vitro. This 2‐part, 2‐period fixed‐sequence study investigated the impact of CYP3A inhibition (itraconazole) and CYP3A induction (rifampin) on the pharmacokinetics (PK) of fruquintinib and M11, its main metabolite.
Martha Gonzalez   +5 more
wiley   +1 more source

Urinalisis Menggunakan Dua Jenis Dipstick (Batang Celup) pada Sapi Bali

open access: yesJurnal Veteriner, 2012
This study aimed to compare two kind of urinalysis dipsticks normaly used for human, for used in balicattle. A total of 100 urine samples were collected from 78 bulls and 22 cows ages between 4-7 years old.Each sample was kept in a plastic bottle and ...
Iwan Harjono Utama   +6 more
doaj  

Comparison between Urine and Cervical High-Risk HPV Tests for Japanese Women with ASC-US

open access: yesDiagnostics, 2021
Most uterine cervical cancers are caused by the persistent infection of the high-risk human papillomavirus (hrHPV). Thus, the hrHPV-DNA test, which examines specimens from the cervix, is the standard screening method as well as cytology in western ...
Hiroyuki Yamazaki   +5 more
doaj   +1 more source

Improving proteinuria screening with mailed smartphone urinalysis testing in previously unscreened patients with hypertension: a randomized controlled trial

open access: yesbioRxiv, 2019
BackgroundProteinuria screening is recommended for patients with hypertension to screen for kidney disease and identify those at elevated risk for cardiovascular disease. However, screening rates among hypertensive patients are low.
J. Leddy   +5 more
semanticscholar   +1 more source

Urinalysis in Children and Adolescents [PDF]

open access: yesDeutsches Ärzteblatt international, 2014
Urinalysis is the most commonly performed biochemical test in infancy and early childhood. The urine sample should be correctly obtained, age-specific aspects should be considered, and age-dependent reference values should be used.This review is based on a selective literature search in electronic databases, textbooks, and guidelines from Germany and ...
Boris Utsch, Günter Klaus
openaire   +3 more sources

Effect of Mild to Moderate Hepatic Impairment on Valemetostat Pharmacokinetics: An Open‐Label, Phase I Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana   +8 more
wiley   +1 more source

Alterations of Serum Biochemical and Urinary Parameters in a Canine Population before and after Intravenous Contrast Administration

open access: yesVeterinary Sciences, 2021
Intravenous iodinated contrast (IVIC) medium is routinely administered to dogs. Scattered information exists regarding the serum biochemical or urinary profiles associated with the administration of IVIC in dogs.
Federica Cagnasso   +9 more
doaj   +1 more source

Urinalysis and determination of the urine protein‐to‐creatinine ratio reference interval in healthy cows

open access: yesJournal of Veterinary Internal Medicine, 2019
Background There are no reference intervals for urinalysis in cattle. Hypothesis/Objectives Characterize the urine of healthy cows, establish urine protein‐to‐creatinine ratio (UPC) reference intervals, and test possible differences among dairy and beef ...
N. Herman   +5 more
semanticscholar   +1 more source

A Randomized Thorough QT Trial Using Concentration‐QT Analysis to Evaluate the Effects of Centanafadine on Cardiac Repolarization

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Centanafadine is a norepinephrine/dopamine/serotonin reuptake inhibitor in development for treatment of attention‐deficit/hyperactivity disorder. This double‐blind, placebo‐ and moxifloxacin‐controlled, 3‐period crossover trial evaluated the effects of centanafadine (EB‐1020) and its metabolite (EB‐10601) on cardiac repolarization in 30 ...
Osman S. Turkoglu   +3 more
wiley   +1 more source

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