Results 81 to 90 of about 106,421 (289)

Perspective: Raman spectroscopy for detection and management of diseases affecting the nervous system

Frontiers in Veterinary Science
Raman spectroscopy (RS) is used increasingly for disease detection, including diseases of the nervous system (CNS). This Perspective presents RS basics and how it has been applied to disease detection.
John L. Robertson, John L. Robertson, John L. Robertson, Amr Sayed Issa, Amr Sayed Issa, Ryan S. Senger, Ryan S. Senger   +6 more
doaj   +1 more source

Urinary markers in heart failure – types, timing and thresholds. European Journal of Heart Failure expert consensus document

European Journal of Heart Failure, EarlyView.
Pathophysiologic mechanisms of heart failure (HF) (i.e. renin–angiotensin–aldosterone system [RAAS], congestion, and inflammation), together with patient‐related factors such as diabetes, hypertension, and chronic kidney disease (CKD), contribute to kidney function decline and glomerular or tubular injury.
Masatake Kobayashi, Biykem Bozkurt, Peder Langeland Myhre, Juan Carlos Lopez Azor, Mateusz Guzik, Gracjan Iwanek, Guillaume Baudry, Marta Cobo‐Marcos, Òscar Miró, Jeroen Dauw, Piotr Ponikowski, Wilfried Mullens, Alberto Palazzuoli, Marco Metra, Jan Biegus   +14 more
wiley   +1 more source

A prospective observational study on the efficacy of procalcitonin as a diagnostic test to exclude lower urinary tract infection and to minimize antibiotic overuse

Urology Annals
Background: Urinary tract infection (UTI) stands out as the third-most common infection following gastrointestinal and respiratory tract infections. Over the past decade, the biomarker procalcitonin (PCT) has gained prominence to facilitate the detection
Swastik Acharya, Sanjukta Mishra, Arpan Ghosh, Shubhransu Patro   +3 more
doaj   +1 more source

Adherence to guideline‐directed medical treatments in heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Cardiovascular Pharmacotherapy

European Journal of Heart Failure, EarlyView.
Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline‐directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication non‐adherence represents a critical barrier limiting real‐world efficacy of GDMT.
Gianluigi Savarese, Felix Lindberg, Antonio Cannata, Marianna Adamo, Giuseppe Ambrosio, Pietro Ameri, Markus S. Anker, Magnus Bäck, Antoni Bayes‐Genis, Tuvia Ben Gal, Frieder Braunschweig, Ovidiu Chioncel, Emilia D'Elia, Hassan El‐Tamimi, Gerasimos Filippatos, Nicolas Girerd, Loreena Hill, Ewa Jankowska, Kamlesh Khunti, Basil S. Lewis, Brenda Moura, Offer Amir, Stefania Paolillo, Massimo Piepoli, Abdulla Shehab, Maggie Simpson, Hadi Skouri, Davide Stolfo, Carlo Gabriele Tocchetti, Cristiana Vitale, Maurizio Volterrani, Stephan von Haehling, Sven Wassmann, Mehmet Birhan Yilmaz, Juan Carlos Kaski, Dobromir Dobrev, Marco Metra, Giuseppe M.C. Rosano   +37 more
wiley   +1 more source

Early detection of active glomerular lesions in dogs and cats using podocin

Journal of Veterinary Research, 2019
In veterinary medicine, sensitive and specific markers of the early stages of renal failure still remain to be established. Podocytes could be a promising diagnostic tool in veterinary nephrology, especially in the differentiation of active pathological ...
Szczepankiewicz Barbara, Pasławska Urszula, Nowak Marcin, Bąchor Remigiusz, Czyżewska-Buczyńska Agnieszka, Pasławski Robert, Szewczuk Zbigniew   +6 more
doaj   +1 more source

A multicenter, open-label, long-term safety and tolerability study of DFN-02, an intranasal spray of sumatriptan 10 mg plus permeation enhancer DDM, for the acute treatment of episodic migraine. [PDF]

, 2017
BackgroundDFN-02 is a novel intranasal spray formulation composed of sumatriptan 10 mg and a permeation-enhancing excipient comprised of 0.2% 1-O-n-Dodecyl-β-D-Maltopyranoside (DDM).
Allenby, Kent, Brand-Schieber, Elimor, Cady, Roger K, Munjal, Sagar, Rapoport, Alan M, Spierings, Egilius LH   +5 more
core   +1 more source

Urea Biosensor Based on a Field‐Effect Capacitor Modified With a Stacked Weak Polyelectrolyte/Enzyme Bilayer

Electrochemical Science Advances, EarlyView.
ABSTRACT Urea is formed from the metabolism of proteins and used as a biomarker for diagnosing and monitoring various medical conditions. In this work, a urea biosensor based on an electrolyte‐insulator‐semiconductor capacitor (EISCAP) modified with a stacked polyelectrolyte polyallylamine hydrochloride (PAH)/urease bilayer prepared by the layer‐by ...
Astghik S. Tsokolakyan, Vardan A. Hayrapetyan, Derenik K. Petrosyan, Melanie Welden, Heiko Iken, Michael J. Schöning, Mkrtich A. Yeranosyan, Arshak Poghossian   +7 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Targeting the Nrf2/TGF‐β1/Smad Signaling Pathway: A Novel Strategy for Urolithin A to Alleviate Renal Fibrosis

Food Frontiers, EarlyView.
The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu, Jiating Li, Yonghui Dong, Jia Li, Ji Bian, Chao Liu, Hongbo Zhang, Lin Han, Min Wang   +8 more
wiley   +1 more source

Assessing the Utility of Ultrasound and Urinalysis for Patients with Possible Epididymo-Orchitis – A Retrospective Study

Open Access Emergency Medicine, 2020
Tony Zitek,1– 3 Omar Ahmed,3 Chee Lim,4 Rianda Carodine,1,5 Kent Martin2 1Department of Emergency Medicine, University Medical Center of Southern Nevada, Las Vegas, NV, USA; 2Department of Emergency Medicine, Kendall Regional Medical Center, Miami,
Zitek T, Ahmed O, Lim C, Carodine R, Martin K   +4 more
doaj